6QCI
Structure of XIAP-BIR1 V86E mutant
Summary for 6QCI
Entry DOI | 10.2210/pdb6qci/pdb |
Related | 4MTZ 4OXC 6GJW |
Descriptor | E3 ubiquitin-protein ligase XIAP, ZINC ION, SODIUM ION, ... (5 entities in total) |
Functional Keywords | bir; nf-kb; xiap; cancer; apoptosis; docking; inhibitor, apoptosis |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 49964.61 |
Authors | Sorrentino, L.,Cossu, F.,Milani, M.,Mastrangelo, E. (deposition date: 2018-12-28, release date: 2019-05-01, Last modification date: 2024-01-24) |
Primary citation | Sorrentino, L.,Cossu, F.,Milani, M.,Malkoc, B.,Huang, W.C.,Tsay, S.C.,Ru Hwu, J.,Mastrangelo, E. Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1. Chemistryopen, 8:476-482, 2019 Cited by PubMed: 31011505DOI: 10.1002/open.201900059 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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