PDB: 52994 resultsInfo pagesStatus searchChemie searchBIRD

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7BAR	Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked) Descriptor: (S,E)-3-(2-(3-bromo-4-hydroxybenzylidene)hydrazineyl)-2-(3-chlorophenyl)-3-oxopropan-1-aminium, cAMP-dependent protein kinase catalytic subunit alpha Authors: Oebbeke, M, Heine, A, Klebe, G. Deposit date: 2020-12-16 Release date: 2022-01-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Crystal structure of the cAMP-dependent protein kinase A with a chiral ligand (S- and E-configuration, soaked) To Be Published
6XB6	Structure of Danaus plexippus poxin cGAMP nuclease Descriptor: Poxin Authors: Eaglesham, J.B, McCarty, K.L, Kranzusch, P.J. Deposit date: 2020-06-05 Release date: 2020-11-25 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife, 9, 2020
8UZN	Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (AMP bound) Descriptor: ADENOSINE MONOPHOSPHATE, Betaine aldehyde dehydrogenase, SODIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-11-15 Release date: 2023-12-06 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure of Betaine aldehyde dehydrogenase (BetB) from Klebsiella aerogenes (AMP bound) To be published
3S22	AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with an inhibitor Descriptor: Beta-lactamase, CHLORIDE ION, [(2S,3R)-2-formyl-1-{[4-(methylamino)butyl]carbamoyl}pyrrolidin-3-yl]sulfamic acid Authors: Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. Deposit date: 2011-05-16 Release date: 2011-06-29 Last modified: 2013-06-26 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
6YX5	Structure of DrrA from Legionella pneumophilia in complex with human Rab8a Descriptor: MAGNESIUM ION, Multifunctional virulence effector protein DrrA, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Schneider, S, Du, J, von Wrisberg, M.K, Lang, K, Itzen, A. Deposit date: 2020-04-30 Release date: 2020-12-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Rab1-AMPylation by Legionella DrrA is allosterically activated by Rab1. Nat Commun, 12, 2021
7C9Q	Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP Descriptor: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION Authors: Huang, Y, Li, R, Wan, J. Deposit date: 2020-06-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.878 Å) Cite: Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP To Be Published
5T8S	Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound S-adenosylmethionine, AMP, Pyrophosphate, Phosphate, and Magnesium Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-09-08 Release date: 2016-09-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound S-adenosylmethionine, AMP, Pyrophosphate, Phosphate, and Magnesium to be published
5T8T	Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, S-adenosylmethionine synthase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-09-08 Release date: 2016-09-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium to be published
7N8W	Crystal structure of ERI2 nuclease bound to rAMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 2, ... Authors: Thapar, R, Arvai, A.S, Tainer, J.A. Deposit date: 2021-06-15 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal structure of ERI2 nuclease bound to rAMP To Be Published
1NJG	Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit Descriptor: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
1NJF	Nucleotide bound form of an isolated E. coli clamp loader gamma subunit Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
3I62	Structure of Mss116p bound to ssRNA and ADP-Aluminum Fluoride Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ... Authors: Del Campo, M, Lambowitz, A.M. Deposit date: 2009-07-06 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA Mol.Cell, 35, 2009
3FJP	Apo structure of Biotin protein ligase from Aquifex aeolicus Descriptor: Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION Authors: McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J. Deposit date: 2008-12-15 Release date: 2009-06-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity. J.Mol.Biol., 387, 2009
3I61	Structure of Mss116p bound to ssRNA and ADP-Beryllium Fluoride Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, ... Authors: Del Campo, M, Lambowitz, A.M. Deposit date: 2009-07-06 Release date: 2009-09-08 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Yeast DEAD box protein Mss116p reveals two wedges that crimp RNA Mol.Cell, 35, 2009
6NO7	Crystal Structure of the full-length wild-type PKA RIa Holoenzyme Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Lu, T, Wu, J, Taylor, S.S. Deposit date: 2019-01-15 Release date: 2019-07-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.55 Å) Cite: Two PKA RI alpha holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proc.Natl.Acad.Sci.USA, 116, 2019
3I59	Crystal structure of MtbCRP in complex with N6-cAMP Descriptor: (2R)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, (2S)-N6-(1-Methyl-2-phenylethyl)adenosine-3',5'-cyclic monophosphate, CHLORIDE ION, ... Authors: Reddy, M.C, Palaninathan, S.K, Bruning, J.B, Thurman, C, Smith, D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2009-07-03 Release date: 2009-09-08 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein. J.Biol.Chem., 284, 2009
6QZR	14-3-3 sigma in complex with FOXO1 pT24 peptide Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Forkhead box protein O1, ... Authors: Ottmann, C, Wolter, M, Lau, R.A. Deposit date: 2019-03-12 Release date: 2019-07-31 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294, 2019
6QZS	14-3-3 sigma in complex with FOXO1 pS256 peptide Descriptor: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FOXO1 pS256 site, ... Authors: Ottmann, C, Wolter, M, Lau, R.A. Deposit date: 2019-03-12 Release date: 2019-07-31 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. J.Biol.Chem., 294, 2019
5XPU	Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a monoclinic crystal Descriptor: Chromosome alignment-maintaining phosphoprotein 1, Mitotic spindle assembly checkpoint protein MAD2B Authors: Hara, K, Taharazako, S, Hashimoto, H. Deposit date: 2017-06-05 Release date: 2017-09-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.304 Å) Cite: Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP). J. Biol. Chem., 292, 2017
7FJ8	KpAckA (PduW) with AMP complex structure Descriptor: ADENOSINE MONOPHOSPHATE, Probable propionate kinase Authors: Wu, W, Zhang, Q, Bartlam, M. Deposit date: 2021-08-03 Release date: 2022-08-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: KpAckA (PduW) with AMP complex structure To Be Published
3SG7	Crystal Structure of GCaMP3-KF(linker 1) Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG5	Crystal Structure of Dimeric GCaMP3-D380Y, QP(linker 1), LP(linker 2) Descriptor: CALCIUM ION, GLYCEROL, Myosin light chain kinase, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG2	Crystal Structure of GCaMP2-T116V,D381Y Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG6	Crystal Structure of Dimeric GCaMP2-LIA(linker 1) Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012
3SG3	Crystal Structure of GCaMP3-D380Y Descriptor: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... Authors: Schreiter, E.R, Akerboom, J, Looger, L.L. Deposit date: 2011-06-14 Release date: 2012-06-20 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Optimization of a GCaMP calcium indicator for neural activity imaging. J.Neurosci., 32, 2012

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