6SI8
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![BU of 6si8 by Molmil](/molmil-images/mine/6si8) | Escherichia coli AGPase in complex with AMP. | Descriptor: | ADENOSINE MONOPHOSPHATE, Glucose-1-phosphate adenylyltransferase | Authors: | Cifuente, J.O, Comino, N, D'Angelo, C, Marina, A, Gil-Carton, D, Albesa-Jove, D, Guerin, M.E. | Deposit date: | 2019-08-09 | Release date: | 2020-02-05 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM. Curr Res Struct Biol, 2, 2020
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6WAZ
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![BU of 6waz by Molmil](/molmil-images/mine/6waz) | +1 extended HIV-1 reverse transcriptase initiation complex core (pre-translocation state) | Descriptor: | HIV-1 viral RNA genome fragment, Reverse transcriptase p51 subunit, Reverse transcriptase/ribonuclease H, ... | Authors: | Larsen, K.P, Jackson, L.N, Kappel, K, Zhang, J, Puglisi, E.V. | Deposit date: | 2020-03-26 | Release date: | 2020-06-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Distinct Conformational States Underlie Pausing during Initiation of HIV-1 Reverse Transcription. J.Mol.Biol., 432, 2020
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6SPB
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![BU of 6spb by Molmil](/molmil-images/mine/6spb) | Pseudomonas aeruginosa 50s ribosome from a clinical isolate with a mutation in uL6 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | Authors: | Halfon, Y, Jimenez-Fernande, A, La Ros, R, Espinos, R, Krogh Johansen, H, Matzov, D, Eyal, Z, Bashan, A, Zimmerman, E, Belousoff, M, Molin, S, Yonath, A. | Deposit date: | 2019-09-01 | Release date: | 2019-10-16 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (2.82 Å) | Cite: | Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate. Proc.Natl.Acad.Sci.USA, 116, 2019
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6VRH
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![BU of 6vrh by Molmil](/molmil-images/mine/6vrh) | Cryo-EM structure of the wild-type human serotonin transporter complexed with paroxetine and 8B6 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | Authors: | Coleman, J.A, Navratna, V, Yang, D. | Deposit date: | 2020-02-07 | Release date: | 2020-03-11 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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5TGZ
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![BU of 5tgz by Molmil](/molmil-images/mine/5tgz) | Crystal Structure of the Human Cannabinoid Receptor CB1 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-[4-[2-(2,4-dichlorophenyl)-4-methyl-5-(piperidin-1-ylcarbamoyl)pyrazol-3-yl]phenyl]but-3-ynyl nitrate, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | Authors: | Hua, T, Vemuri, K, Pu, M, Qu, L, Han, G.W, Wu, Y, Zhao, S, Shui, W, Li, S, Korde, A, Laprairie, R.B, Stahl, E.L, Ho, J.H, Zvonok, N, Zhou, H, Kufareva, I, Wu, B, Zhao, Q, Hanson, M.A, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | Deposit date: | 2016-09-28 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Human Cannabinoid Receptor CB1. Cell, 167, 2016
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6SJ6
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![BU of 6sj6 by Molmil](/molmil-images/mine/6sj6) | Cryo-EM structure of 50S-RsfS complex from Staphylococcus aureus | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Khusainov, I, Pellegrino, S, Yusupova, G, Yusupov, M, Fatkhullin, B. | Deposit date: | 2019-08-12 | Release date: | 2020-04-08 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Mechanism of ribosome shutdown by RsfS in Staphylococcus aureus revealed by integrative structural biology approach. Nat Commun, 11, 2020
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6VI4
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![BU of 6vi4 by Molmil](/molmil-images/mine/6vi4) | Nanobody-Enabled Monitoring of Kappa Opioid Receptor States | Descriptor: | (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, CHOLESTEROL, Kappa opioid receptor, ... | Authors: | Che, T, Roth, B.L. | Deposit date: | 2020-01-11 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun, 11, 2020
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6VS8
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![BU of 6vs8 by Molmil](/molmil-images/mine/6vs8) | |
2MUQ
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![BU of 2muq by Molmil](/molmil-images/mine/2muq) | Solution Structure of the Human FAAP20 UBZ | Descriptor: | Fanconi anemia-associated protein of 20 kDa, ZINC ION | Authors: | Wojtaszek, J.L, Wang, S, Zhou, P. | Deposit date: | 2014-09-16 | Release date: | 2014-12-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. Nucleic Acids Res., 42, 2014
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6RNJ
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![BU of 6rnj by Molmil](/molmil-images/mine/6rnj) | TR-SMX closed state structure (0-5ms) of bacteriorhodopsin | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Weinert, T, Skopintsev, P, James, D, Kekilli, D, Furrer, F, Bruenle, S, Mous, S, Nogly, P, Standfuss, J. | Deposit date: | 2019-05-08 | Release date: | 2019-07-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography. Science, 365, 2019
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2N2M
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![BU of 2n2m by Molmil](/molmil-images/mine/2n2m) | |
5T9M
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![BU of 5t9m by Molmil](/molmil-images/mine/5t9m) | Structure of rabbit RyR1 (Ca2+-only dataset, class 1) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | Authors: | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | Deposit date: | 2016-09-09 | Release date: | 2016-10-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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2MW9
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![BU of 2mw9 by Molmil](/molmil-images/mine/2mw9) | |
5TAY
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![BU of 5tay by Molmil](/molmil-images/mine/5tay) | Structure of rabbit RyR1 (ryanodine dataset, class 2) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | Authors: | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | Deposit date: | 2016-09-10 | Release date: | 2016-10-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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6RQJ
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![BU of 6rqj by Molmil](/molmil-images/mine/6rqj) | Structure of human complement C5 complexed with tick inhibitors OmCI, RaCI1 and CirpT1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5, Complement inhibitor, ... | Authors: | Reichhardt, M.P, Johnson, S, Lea, S.M. | Deposit date: | 2019-05-15 | Release date: | 2020-01-08 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An inhibitor of complement C5 provides structural insights into activation. Proc.Natl.Acad.Sci.USA, 117, 2020
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8GOF
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![BU of 8gof by Molmil](/molmil-images/mine/8gof) | Structure of hSLC19A1+PMX | Descriptor: | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Reduced folate transporter | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-08-24 | Release date: | 2022-10-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
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8GOE
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![BU of 8goe by Molmil](/molmil-images/mine/8goe) | Structure of hSLC19A1+5-MTHF | Descriptor: | N-[4-({[(6S)-2-AMINO-4-HYDROXY-5-METHYL-5,6,7,8-TETRAHYDROPTERIDIN-6-YL]METHYL}AMINO)BENZOYL]-L-GLUTAMIC ACID, Reduced folate transporter | Authors: | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | Deposit date: | 2022-08-24 | Release date: | 2022-10-05 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612, 2022
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6VQU
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![BU of 6vqu by Molmil](/molmil-images/mine/6vqu) | Structure of a bacterial Atm1-family ABC exporter | Descriptor: | ATM1-type heavy metal exporter | Authors: | Fan, C, Rees, D.C. | Deposit date: | 2020-02-05 | Release date: | 2020-07-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | A structural framework for unidirectional transport by a bacterial ABC exporter. Proc.Natl.Acad.Sci.USA, 117, 2020
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8GVM
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![BU of 8gvm by Molmil](/molmil-images/mine/8gvm) | The structure of azide-bound cytochrome C oxidase determined using the crystals exposed to 20 mm azide solution for 4 days | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Tsukihara, T, Shimada, A. | Deposit date: | 2022-09-15 | Release date: | 2022-10-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.851 Å) | Cite: | X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity J. Biol. Chem., 293, 2018
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6VSF
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![BU of 6vsf by Molmil](/molmil-images/mine/6vsf) | Mycobacterium tuberculosis dihydrofolate reductase in complex with 4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-4-oxobutanoic acid(fragment 16) | Descriptor: | 4-(3,4-dihydro-2H-1,5-benzodioxepin-7-yl)-4-oxobutanoic acid, COBALT (II) ION, Dihydrofolate reductase, ... | Authors: | Ribeiro, J.A, Dias, M.V.B. | Deposit date: | 2020-02-11 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.012 Å) | Cite: | Using a Fragment-Based Approach to Identify Alternative Chemical Scaffolds Targeting Dihydrofolate Reductase fromMycobacterium tuberculosis. Acs Infect Dis., 6, 2020
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6RT4
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![BU of 6rt4 by Molmil](/molmil-images/mine/6rt4) | |
6VWM
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![BU of 6vwm by Molmil](/molmil-images/mine/6vwm) | 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure I) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | Deposit date: | 2020-02-20 | Release date: | 2020-06-03 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding. Elife, 9, 2020
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6VZ2
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![BU of 6vz2 by Molmil](/molmil-images/mine/6vz2) | Escherichia coli transcription-translation complex D1 (TTC-D1) containing mRNA with a 27 nt long spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6RU1
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![BU of 6ru1 by Molmil](/molmil-images/mine/6ru1) | Crystal Structure of Glucuronoyl Esterase from Cerrena unicolor inactive S270A variant in complex with the aldouronic acid Um4X | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ... | Authors: | Ernst, H.A, Mosbech, C, Langkilde, A, Westh, P, Meyer, A, Agger, J.W, Larsen, S. | Deposit date: | 2019-05-27 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | The structural basis of fungal glucuronoyl esterase activity on natural substrates. Nat Commun, 11, 2020
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6VYU
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![BU of 6vyu by Molmil](/molmil-images/mine/6vyu) | Escherichia coli transcription-translation complex C2 (TTC-C2) containing a 27 nt long mRNA spacer | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-02-27 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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