8GOF

Structure of hSLC19A1+PMX

Summary for 8GOF

Entry DOI	10.2210/pdb8gof/pdb
EMDB information	34177
Descriptor	Reduced folate transporter, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID (2 entities in total)
Functional Keywords	hslc19a1+pmx complex, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	60983.49
Authors	Zhang, Q.X.,Zhang, X.Y.,Zhu, Y.L.,Sun, P.P.,Gao, A.,Zhang, L.G.,Gao, P. (deposition date: 2022-08-24, release date: 2022-10-05, Last modification date: 2022-12-14)
Primary citation	Zhang, Q.,Zhang, X.,Zhu, Y.,Sun, P.,Zhang, L.,Ma, J.,Zhang, Y.,Zeng, L.,Nie, X.,Gao, Y.,Li, Z.,Liu, S.,Lou, J.,Gao, A.,Zhang, L.,Gao, P. Recognition of cyclic dinucleotides and folates by human SLC19A1. Nature, 612:170-176, 2022 Cited by PubMed: 36265513 DOI: 10.1038/s41586-022-05452-z PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation