6VI4

Nanobody-Enabled Monitoring of Kappa Opioid Receptor States

Summary for 6VI4

Entry DOI	10.2210/pdb6vi4/pdb
Descriptor	Kappa opioid receptor, Nanobody 6, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, ... (4 entities in total)
Functional Keywords	g protein-coupled opioid receptor, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	100409.22
Authors	Che, T.,Roth, B.L. (deposition date: 2020-01-11, release date: 2020-03-18, Last modification date: 2023-10-11)
Primary citation	Che, T.,English, J.,Krumm, B.E.,Kim, K.,Pardon, E.,Olsen, R.H.J.,Wang, S.,Zhang, S.,Diberto, J.F.,Sciaky, N.,Carroll, F.I.,Steyaert, J.,Wacker, D.,Roth, B.L. Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun, 11:1145-1145, 2020 Cited by PubMed: 32123179 DOI: 10.1038/s41467-020-14889-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation