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6VWM

70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure I)

This is a non-PDB format compatible entry.
Summary for 6VWM
Entry DOI10.2210/pdb6vwm/pdb
EMDB information21421
Descriptor5S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (54 entities in total)
Functional Keywordshiv fss, frameshifting, ribosome
Biological sourceEscherichia coli
More
Total number of polymer chains53
Total formula weight2187196.93
Authors
Loerch, S.,Bao, C.,Ling, C.,Korostelev, A.A.,Grigorieff, N.,Ermolenko, D.M. (deposition date: 2020-02-20, release date: 2020-06-03)
Primary citationBao, C.,Loerch, S.,Ling, C.,Korostelev, A.A.,Grigorieff, N.,Ermolenko, D.N.
mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Elife, 9:-, 2020
Cited by
PubMed: 32427100
DOI: 10.7554/eLife.55799
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.4 Å)
Structure validation

221371

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