3UQ0
 
 | | Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus. | | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*AP*GP*TP*AP*CP)-R(P*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', ... | | Authors: | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda
Nucleic Acids Res., 40, 2012
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2ACE
 | | NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA | | Descriptor: | ACETYLCHOLINE, ACETYLCHOLINESTERASE | | Authors: | Harel, M, Raves, M.L, Silman, I, Sussman, J.L. | | Deposit date: | 1996-06-23 | | Release date: | 1996-11-08 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A.
Nat.Struct.Biol., 4, 1997
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4PRY
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5KOY
 | | Mouse pgp 34 linker deleted bound with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-07-01 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.85 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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5KO2
 | | Mouse pgp 34 linker deleted mutant Hg derivative | | Descriptor: | MERCURY (II) ION, Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-06-29 | | Release date: | 2016-11-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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5D4Y
 | | A psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase | | Descriptor: | beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, xylanase | | Authors: | Zheng, Y, Guo, R.T. | | Deposit date: | 2015-08-10 | | Release date: | 2016-02-24 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural insight into potential cold adaptation mechanism through a psychrophilic glycoside hydrolase family 10 endo-beta-1,4-xylanase.
J.Struct.Biol., 193, 2016
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4Q3M
 | | Crystal structure of MGS-M4, an aldo-keto reductase enzyme from a Medee basin deep-sea metagenome library | | Descriptor: | MGS-M4, SODIUM ION, SULFATE ION | | Authors: | Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. | | Deposit date: | 2014-04-11 | | Release date: | 2015-02-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.552 Å) | | Cite: | Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats.
Environ Microbiol, 17, 2015
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5KPD
 | | Mouse pgp 34 linker deleted double EQ mutant | | Descriptor: | Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-07-03 | | Release date: | 2016-11-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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3UQ2
 | | Crystal structure of the post-catalytic product complex of polymerase lambda with an rCMP inserted opposite a templating G and dAMP inserted opposite a templating T at the primer terminus. | | Descriptor: | 5'-D(*CP*AP*GP*TP*AP)-R(P*CP*A)-3', 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3', 5'-D(P*GP*CP*CP*G)-3', ... | | Authors: | Gosavi, R.A, Moon, A.F, Kunkel, T.A, Pedersen, L.C, Bebenek, K. | | Deposit date: | 2011-11-18 | | Release date: | 2012-05-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The catalytic cycle for ribonucleotide incorporation by human DNA Pol lambda
Nucleic Acids Res., 40, 2012
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5X40
 | | Structure of a CbiO dimer bound with AMPPCP | | Descriptor: | Cobalt ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | Authors: | Bao, Z, Qi, X, Wang, J, Zhang, P. | | Deposit date: | 2017-02-09 | | Release date: | 2017-04-05 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and mechanism of a group-I cobalt energy coupling factor transporter
Cell Res., 27, 2017
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5KPI
 | | Mouse native PGP | | Descriptor: | Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-07-04 | | Release date: | 2016-11-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.01 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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1YWM
 | | Crystal structure of the N-terminal domain of group B Streptococcus alpha C protein | | Descriptor: | (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, C protein alpha-antigen, GLYCEROL | | Authors: | Auperin, T.C, Bolduc, G.R, Baron, M.J, Heroux, A, Filman, D.J, Madoff, L.C, Hogle, J.M. | | Deposit date: | 2005-02-18 | | Release date: | 2005-03-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of the N-terminal domain of the group B streptococcus alpha C protein.
J.Biol.Chem., 280, 2005
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3V51
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4A0D
 | | Structure of unliganded human PARG catalytic domain | | Descriptor: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, POLY(ADP-RIBOSE) GLYCOHYDROLASE, ... | | Authors: | Brassington, C, Ellston, J, Hassall, G, Holdgate, G, McAlister, M, Overman, R, Smith, G, Tucker, J.A, Watson, M. | | Deposit date: | 2011-09-08 | | Release date: | 2012-10-17 | | Last modified: | 2013-01-16 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structures of the Human Poly (Adp-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by Adp-Hpd Derivatives.
Plos One, 7, 2012
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5XF8
 | | Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state | | Descriptor: | Cell division cycle protein CDT1, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... | | Authors: | Zhai, Y, Cheng, E, Wu, H, Li, N, Yung, P.Y, Gao, N, Tye, B.K. | | Deposit date: | 2017-04-09 | | Release date: | 2017-05-03 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer
Nat. Struct. Mol. Biol., 24, 2017
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1ZKM
 | | Structural Analysis of Escherichia Coli ThiF | | Descriptor: | Adenylyltransferase thiF, ZINC ION | | Authors: | Duda, D.M, Walden, H, Sfondouris, J, Schulman, B.A. | | Deposit date: | 2005-05-03 | | Release date: | 2005-06-14 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
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5GAS
 | | Thermus thermophilus V/A-ATPase, conformation 2 | | Descriptor: | Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | Authors: | Schep, D.G, Zhao, J, Rubinstein, J.L. | | Deposit date: | 2016-02-05 | | Release date: | 2016-03-09 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (9.5 Å) | | Cite: | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3BY7
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5GAI
 | | Probabilistic Structural Models of Mature P22 Bacteriophage Portal, Hub, and Tailspike proteins | | Descriptor: | Peptidoglycan hydrolase gp4, Portal protein, Tail fiber protein | | Authors: | Pintilie, G, Chen, D.H, Haase-Pettingell, C.A, King, J.A, Chiu, W. | | Deposit date: | 2015-12-01 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (10.5 Å) | | Cite: | Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage.
Biophys.J., 110, 2016
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1M4U
 | | Crystal structure of Bone Morphogenetic Protein-7 (BMP-7) in complex with the secreted antagonist Noggin | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone Morphogenetic Protein-7, Noggin | | Authors: | Groppe, J, Greenwald, J, Wiater, E, Rodriguez-Leon, J, Economides, A.N, Kwiatkowski, W, Affolter, M, Vale, W.W, Izpisua-Belmonte, J.C, Choe, S. | | Deposit date: | 2002-07-03 | | Release date: | 2002-12-18 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structural Basis of BMP Signalling Inhibition by the Cystine Knot Protein Noggin
Nature, 420, 2002
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1MC0
 | | Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains | | Descriptor: | 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE | | Authors: | Martinez, S, Wu, A, Glavas, N, Tang, X, Turley, S, Hol, W, Beavo, J. | | Deposit date: | 2002-08-04 | | Release date: | 2002-10-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
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3V5T
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3UM1
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2A1E
 | | High resolution structure of HIV-1 PR with TS-126 | | Descriptor: | ACETATE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Demitri, N, Geremia, S, Randaccio, L, Wuerges, J, Benedetti, F, Berti, F, Dinon, F, Campaner, P, Tell, G. | | Deposit date: | 2005-06-20 | | Release date: | 2006-02-21 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | A potent HIV protease inhibitor identified in an epimeric mixture by high-resolution protein crystallography.
Chemmedchem, 1, 2006
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3UM0
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