PDB: 46169 resultsInfo pagesStatus searchChemie searchBIRD

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6LWL	Crystal structure of human NEIL1(R242) bound to duplex DNA containing 2'-fluoro-2'-deoxy-5,6-dihydrouridine Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(FDU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ... Authors: Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. Deposit date: 2020-02-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.55 Å) Cite: DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
6LWR	Crystal structure of human NEIL1(K242) bound to duplex DNA containing a cleaved C:T mismatch Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*(PDA))-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 Authors: Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. Deposit date: 2020-02-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.9 Å) Cite: DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
5GUJ	Crystal structure of the Bacillus subtilis DnaG RNA Polymerase Domain, natural degradation of full length DnaG Descriptor: DNA primase Authors: Zhou, Y, Liu, Z, Wang, G. Deposit date: 2016-08-29 Release date: 2017-04-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria Sci Rep, 7, 2017
6LWJ	Crystal structure of human NEIL1(P2G, E3Q, K242) bound to duplex DNA containing dihydrouracil (DHU) Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(UDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ... Authors: Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. Deposit date: 2020-02-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.83 Å) Cite: DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
6LWK	Crystal structure of human NEIL1(P2G, E3Q, R242) bound to duplex DNA containing dihydrouracil (DHU) Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(UDH)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1, ... Authors: Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. Deposit date: 2020-02-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.88 Å) Cite: DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
3U3Y	Mouse TREX1 D200H mutant Descriptor: 1,4-BUTANEDIOL, 5'-D(*GP*AP*CP*G)-3', CALCIUM ION, ... Authors: Bailey, S.L, Harvey, S, Perrino, F.W, Hollis, T. Deposit date: 2011-10-06 Release date: 2011-12-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease. Dna Repair, 11, 2012
3U6F	Mouse TREX1 D200N mutant Descriptor: 1,4-BUTANEDIOL, 5'-D(*GP*AP*CP*G)-3', MAGNESIUM ION, ... Authors: Bailey, S.L, Harvey, S, Perrino, F.W, Hollis, T. Deposit date: 2011-10-12 Release date: 2011-12-28 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease. Dna Repair, 11, 2012
1D17	DNA-NOGALAMYCIN INTERACTIONS Descriptor: DNA (5'-D(*(5CM)P*GP*TP*AP*(5CM)P*G)-3'), NOGALAMYCIN Authors: Egli, M, Williams, L.D, Frederick, C.A, Rich, A. Deposit date: 1990-08-08 Release date: 1991-07-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: DNA-nogalamycin interactions. Biochemistry, 30, 1991
4CRO	PROTEIN-DNA CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURE OF A LAMBDA CRO-OPERATOR COMPLEX Descriptor: DNA (5'-D(*TP*AP*TP*CP*AP*CP*CP*GP*CP*GP*GP*GP*TP*GP*AP*TP*A)-3'), PROTEIN (LAMBDA CRO) Authors: Brennan, R.G, Roderick, S.L, Takeda, Y, Matthews, B.W. Deposit date: 1992-01-15 Release date: 1992-01-15 Last modified: 2022-11-23 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex. Proc.Natl.Acad.Sci.USA, 87, 1990
6CBR	DnaG Primase C-terminal domain complex with SSB C-terminal peptide Descriptor: DNA primase,single-stranded DNA-binding protein chimera Authors: Oakley, A.J, Lo, A.T.Y. Deposit date: 2018-02-05 Release date: 2019-02-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.5 Å) Cite: DnaG Primase C-terminal domain complex with SSB C-terminal peptide To be Published
2DNJ	DNASE I-INDUCED DNA CONFORMATION. 2 ANGSTROMS STRUCTURE OF A DNASE I-OCTAMER COMPLEX Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-D(*GP*CP*GP*AP*TP*C)-3', 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', ... Authors: Lahm, A, Suck, D. Deposit date: 1986-10-21 Release date: 1994-01-31 Last modified: 2020-10-21 Method: X-RAY DIFFRACTION (2 Å) Cite: DNase I-induced DNA conformation. 2 A structure of a DNase I-octamer complex J.Mol.Biol., 222, 1991
4NRV	Crystal Structure of non-edited human NEIL1 Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endonuclease 8-like 1 Authors: Prakash, A, Doublie, S. Deposit date: 2013-11-27 Release date: 2014-01-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Genome and cancer single nucleotide polymorphisms of the human NEIL1 DNA glycosylase: Activity, structure, and the effect of editing. Dna Repair, 14, 2014
2V79	Crystal Structure of the N-terminal domain of DnaD from Bacillus Subtilis Descriptor: CHLORIDE ION, DNA REPLICATION PROTEIN DNAD, SODIUM ION Authors: Schneider, S, Zhang, W, Soultanas, P, Paoli, M. Deposit date: 2007-07-27 Release date: 2008-01-15 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of the N-Terminal Oligomerization Domain of Dnad Reveals a Unique Tetramerization Motif and Provides Insights Into Scaffold Formation. J.Mol.Biol., 376, 2008
6LWQ	Crystal structure of human NEIL1(R242) bound to duplex DNA containing a C:T mismatch Descriptor: DNA (5'-D(*CP*GP*TP*CP*CP*AP*TP*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3'), Endonuclease 8-like 1 Authors: Liu, M.H, Zhang, J, Zhu, C.X, Zhang, X.X, Gao, Y.Q, Yi, C.Q. Deposit date: 2020-02-07 Release date: 2021-06-09 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.89 Å) Cite: DNA repair glycosylase hNEIL1 triages damaged bases via competing interaction modes. Nat Commun, 12, 2021
245D	DNA-DRUG REFINEMENT: A COMPARISON OF THE PROGRAMS NUCLSQ, PROLSQ, SHELXL93 AND X-PLOR, USING THE LOW TEMPERATURE D(TGATCA)-NOGALAMYCIN STRUCTURE Descriptor: DNA (5'-D(*TP*GP*AP*TP*CP*A)-3'), NOGALAMYCIN Authors: Schuerman, G.S, Smith, C.K, Turkenburg, J.P, Dettmar, A.N, Van Meervelt, L, Moore, M.H. Deposit date: 1996-01-12 Release date: 1996-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.4 Å) Cite: DNA-drug refinement: a comparison of the programs NUCLSQ, PROLSQ, SHELXL93 and X-PLOR, using the low-temperature d(TGATCA)-nogalamycin structure. Acta Crystallogr.,Sect.D, 52, 1996
224D	DNA-DRUG REFINEMENT: A COMPARISON OF THE PROGRAMS NUCLSQ, PROLSQ, SHELXL93 AND X-PLOR, USING THE LOW TEMPERATURE D(TGATCA)-NOGALAMYCIN STRUCTURE Descriptor: DNA (5'-D(*TP*GP*AP*TP*CP*A)-3'), NOGALAMYCIN Authors: Schuerman, G.S, Smith, C.K, Turkenburg, J.P, Dettmar, A.N, Van Meervelt, L, Moore, M.H. Deposit date: 1995-08-01 Release date: 1995-11-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.4 Å) Cite: DNA-drug refinement: a comparison of the programs NUCLSQ, PROLSQ, SHELXL93 and X-PLOR, using the low-temperature d(TGATCA)-nogalamycin structure. Acta Crystallogr.,Sect.D, 52, 1996
3KUY	DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumor Agent Descriptor: 2-[(2R)-oxiran-2-ylmethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, DNA (145-MER), Histone H2A, ... Authors: Wu, B, Davey, C.A. Deposit date: 2009-11-28 Release date: 2010-01-05 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: DNA stretching in the nucleosome facilitates alkylation by an intercalating antitumour agent Nucleic Acids Res., 38, 2010
6FFR	DNA-RNA Hybrid Quadruplex with Flipped Tetrad Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3') Authors: Haase, L, Dickerhoff, J, Weisz, K. Deposit date: 2018-01-09 Release date: 2018-09-26 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies. Chemistry, 24, 2018
5W35	Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang Descriptor: DNA primase, synthetic DNA oligomer 5'-CCACTTCCGGTC, synthetic DNA oligomer 5'-TGACCGGAAGTGG Authors: Hou, C, Tsodikov, O.V. Deposit date: 2017-06-07 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.31 Å) Cite: Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry, 57, 2018
5W34	Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with double-stranded DNA GACCGGAAGTGG Descriptor: DNA oligomer 5'-CCACTTCCGGTC, DNA oligomer 5'-GACCGGAAGTGG, DNA primase Authors: Hou, C, Tsodikov, O.V. Deposit date: 2017-06-07 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry, 57, 2018
5W36	Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 6-nucleotide overhang Descriptor: DNA primase, STRONTIUM ION, synthetic DNA 5'-TATCGTCCCGCCTC Authors: Hou, C, Tsodikov, O.V. Deposit date: 2017-06-07 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.46 Å) Cite: Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry, 57, 2018
6TEM	CENP-A nucleosome core particle with 145 base pairs of the Widom 601 sequence by cryo-EM Descriptor: Histone H2A, Histone H2B 1.1, Histone H3-like centromeric protein A, ... Authors: Boopathi, R, Danev, R, Petosa, C, Bednar, J. Deposit date: 2019-11-12 Release date: 2020-04-08 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends. Nucleic Acids Res., 48, 2020
5W33	Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG Descriptor: DNA primase, SULFATE ION Authors: Hou, C, Biswas, T, Tsodikov, O.V. Deposit date: 2017-06-07 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry, 57, 2018
1EMJ	URACIL-DNA GLYCOSYLASE BOUND TO DNA CONTAINING A 4'-THIO-2'DEOXYURIDINE ANALOG PRODUCT Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*(ASU)P*AP*TP*CP*TP*T)-3'), URACIL, ... Authors: Parikh, S.S, Walcher, G, Jones, G.D, Slupphaug, G, Krokan, H.E, Blackburn, G.M, Tainer, J.A. Deposit date: 2000-03-16 Release date: 2000-05-16 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects. Proc.Natl.Acad.Sci.USA, 97, 2000
5E50	APLF/XRCC4 complex Descriptor: Aprataxin and PNK-like factor, MAGNESIUM ION, XRCC4 Authors: Cherry, A.L, Smerdon, S.J. Deposit date: 2015-10-07 Release date: 2015-11-18 Method: X-RAY DIFFRACTION (1.376 Å) Cite: Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains. DNA Repair (Amst.), 35, 2015

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