5W35

Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 1-nucleotide overhang

Summary for 5W35

Entry DOI	10.2210/pdb5w35/pdb
Related	5W33 5W34 5w36
Descriptor	DNA primase, synthetic DNA oligomer 5'-CCACTTCCGGTC, synthetic DNA oligomer 5'-TGACCGGAAGTGG (3 entities in total)
Functional Keywords	dna replication, replisome, toprim fold, dna binding, transferase-dna complex, transferase/dna
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Total number of polymer chains	4
Total formula weight	78531.80
Authors	Hou, C.,Tsodikov, O.V. (deposition date: 2017-06-07, release date: 2018-03-28, Last modification date: 2023-10-04)
Primary citation	Hou, C.,Biswas, T.,Tsodikov, O.V. Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events. Biochemistry, 57:2084-2093, 2018 Cited by PubMed: 29558114 DOI: 10.1021/acs.biochem.8b00036 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.31 Å)

Structure validation