6TEM

CENP-A nucleosome core particle with 145 base pairs of the Widom 601 sequence by cryo-EM

Summary for 6TEM

• Entry DOI: 10.2210/pdb6tem/pdb
• EMDB information: 10822
• Descriptor: Histone H3-like centromeric protein A, Histone H4, Histone H2A, ... (6 entities in total)
• Functional Keywords: cenp-a nucleosome, protein-dna complex, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 199974.75

Authors

Boopathi, R.,Danev, R.,Petosa, C.,Bednar, J. (deposition date: 2019-11-12, release date: 2020-04-08, Last modification date: 2020-06-10)

• Primary citation: Boopathi, R.,Danev, R.,Khoshouei, M.,Kale, S.,Nahata, S.,Ramos, L.,Angelov, D.,Dimitrov, S.,Hamiche, A.,Petosa, C.,Bednar, J.; Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends.; Nucleic Acids Res., 48:5735-5748, 2020; PubMed: 32313946; DOI: 10.1093/nar/gkaa246

Experimental method

ELECTRON MICROSCOPY (3.9 Å)