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6TEM

CENP-A nucleosome core particle with 145 base pairs of the Widom 601 sequence by cryo-EM

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, E
(A, E)
Histone H3-like centromeric protein Apolymer14016023.62UniProt (P49450)
Pfam (PF00125)
Homo sapiens (Human)Centromere autoantigen A,Centromere protein A,CENP-A
2B, F
(B, F)
Histone H4polymer10311394.42UniProt (P62799)
Pfam (PF15511)
Xenopus laevis (African clawed frog)
3C, G
(C, G)
Histone H2Apolymer12913978.22UniProt (Q6AZJ8)
Pfam (PF00125)
Pfam (PF16211)
UniProt (by SIFTS) (P06897)
Xenopus laevis (African clawed frog)
4D, H
(D, H)
Histone H2B 1.1polymer12513834.12UniProt (P02281)
Pfam (PF00125)
Xenopus laevis (African clawed frog)H2B1.1
5I
(I)
Widom 601 DNA (145-MER, sense)polymer14544552.41synthetic construct
6J
(J)
Widom 601 DNA (145-MER, antisense)polymer14544961.61synthetic construct
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight199974.7
All*Total formula weight199974.7
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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