3U6F

Mouse TREX1 D200N mutant

Summary for 3U6F

• Entry DOI: 10.2210/pdb3u6f/pdb
• Descriptor: Three prime repair exonuclease 1, 5'-D(*GP*AP*CP*G)-3', 1,4-BUTANEDIOL, ... (5 entities in total)
• Functional Keywords: rnase h fold, 3' exonuclease, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (mouse)
• Cellular location: Nucleus (By similarity): Q91XB0
• Total number of polymer chains: 4
• Total formula weight: 70079.35

Authors

Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T. (deposition date: 2011-10-12, release date: 2011-12-28, Last modification date: 2024-02-28)

• Primary citation: Bailey, S.L.,Harvey, S.,Perrino, F.W.,Hollis, T.; Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease.; Dna Repair, 11:65-73, 2012; PubMed: 22071149; DOI: 10.1016/j.dnarep.2011.10.007

Experimental method

X-RAY DIFFRACTION (2.3 Å)