5W36

Crystal structure of the RNA polymerase domain (RPD) of Mycobacterium tuberculosis primase DnaG in complex with a double-stranded DNA oligomer with a 6-nucleotide overhang

Summary for 5W36

• Entry DOI: 10.2210/pdb5w36/pdb
• Related: 5W33 5W34 5W35
• Descriptor: DNA primase, synthetic DNA 5'-TATCGTCCCGCCTC, STRONTIUM ION, ... (4 entities in total)
• Functional Keywords: dna replication, replisome, toprim fold, dna binding, transferase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); More
• Total number of polymer chains: 3
• Total formula weight: 75156.14

Authors

Hou, C.,Tsodikov, O.V. (deposition date: 2017-06-07, release date: 2018-03-28, Last modification date: 2023-10-04)

• Primary citation: Hou, C.,Biswas, T.,Tsodikov, O.V.; Structures of the Catalytic Domain of Bacterial Primase DnaG in Complexes with DNA Provide Insight into Key Priming Events.; Biochemistry, 57:2084-2093, 2018; PubMed: 29558114; DOI: 10.1021/acs.biochem.8b00036

Experimental method

X-RAY DIFFRACTION (2.46 Å)