4PRR
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4QIU
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4Y6A
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4Y80
| Yeast 20S proteasome in complex with Ac-LAI-ep | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAI-ep, CHLORIDE ION, ... | Authors: | Huber, E.M, Groll, M. | Deposit date: | 2015-02-16 | Release date: | 2015-06-17 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
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4YA7
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4E7L
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4NJR
| Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | CARBONATE ION, Probable M18 family aminopeptidase 2, ZINC ION | Authors: | Nguyen, D.D, Pandian, R, Kim, D.Y, Ha, S.C, Yun, K.H, Kim, K.S, Kim, J.H, Kim, K.K. | Deposit date: | 2013-11-11 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4EB3
| Crystal structure of IspH in complex with iso-HMBPP | Descriptor: | 3-(hydroxymethyl)but-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER | Authors: | Wang, W, Wang, K, Span, I, Bacher, A, Groll, M, Oldfield, E. | Deposit date: | 2012-03-23 | Release date: | 2013-02-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation. J.Am.Chem.Soc., 134, 2012
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4NX2
| Crystal structure of DCYRS complexed with DCY | Descriptor: | 3,5-dichloro-L-tyrosine, Tyrosine--tRNA ligase | Authors: | Wang, J, Gong, W, Li, J, Gao, F, Li, H. | Deposit date: | 2013-12-08 | Release date: | 2014-09-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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4Z1T
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4Z15
| MIF in complex with 3-(2-furylmethyl)-2-thioxo-1,3-thiazolan-4-one | Descriptor: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION | Authors: | Cho, T.Y. | Deposit date: | 2015-03-26 | Release date: | 2016-09-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J. Cell. Mol. Med., 21, 2017
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4NXE
| Crystal structure of iLOV-I486(2LT) at pH 6.5 | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | Authors: | Wang, J, Liu, X, Li, J. | Deposit date: | 2013-12-09 | Release date: | 2014-09-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers. J.Am.Chem.Soc., 136, 2014
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4NJQ
| Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CARBONATE ION, COBALT (II) ION, ... | Authors: | Nguyen, D.D, Pandian, R, Kim, D.Y, Ha, S.C, Yun, K.H, Kim, K.S, Kim, J.H, Kim, K.K. | Deposit date: | 2013-11-11 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4NFG
| K13R mutant of horse cytochrome c and yeast cytochrome c peroxidase complex | Descriptor: | Cytochrome c, Cytochrome c peroxidase, mitochondrial, ... | Authors: | Meulenbroek, E.M, Bashir, Q, Ubbink, M, Pannu, N.S. | Deposit date: | 2013-10-31 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Engineering specificity in a dynamic protein complex with a single conserved mutation. Febs J., 281, 2014
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5NP8
| PGK1 in complex with CRT0063465 (3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid) | Descriptor: | 1,2-ETHANEDIOL, 3-PHOSPHOGLYCERIC ACID, 3-[2-(4-bromophenyl)-5,7-dimethyl-pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid, ... | Authors: | Turnbull, A.P, Bilsland, A.E, Liu, Y, Sumpton, D, Stevenson, K, Cairney, C.J, Roffey, J, Jenkinson, D, Keith, W.N. | Deposit date: | 2017-04-13 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation. Neoplasia, 21, 2019
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4F15
| Molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses | Descriptor: | Fab fragment, heavy chain, light chain, ... | Authors: | Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I. | Deposit date: | 2012-05-06 | Release date: | 2013-05-15 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses To be Published
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4F1P
| Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1 | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... | Authors: | Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. | Deposit date: | 2012-05-07 | Release date: | 2012-07-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
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4ZDZ
| Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140F mutant complexed with fluconazole | Descriptor: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sagatova, A, Keniya, M.V, Wilson, R.K, Tyndall, J.D.A, Monk, B.C. | Deposit date: | 2015-04-20 | Release date: | 2016-03-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
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4O6Z
| Crystal structure of serine hydroxymethyltransferase with covalently bound PLP Schiff-base from Plasmodium falciparum | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase | Authors: | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U. | Deposit date: | 2013-12-24 | Release date: | 2014-06-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities. Acta Crystallogr.,Sect.D, 70, 2014
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4OID
| Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa | Descriptor: | Probable M18 family aminopeptidase 2 | Authors: | Nguyen, D.D, Pandian, R, Kim, D.D, Ha, S.C, Yoon, H.J, Kim, K.S, Yun, K.H, Kim, J.H, Kim, K.K. | Deposit date: | 2014-01-19 | Release date: | 2014-04-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and kinetic bases for the metal preference of the M18 aminopeptidase from Pseudomonas aeruginosa Biochem.Biophys.Res.Commun., 447, 2014
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4ZE3
| Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140H mutant complexed with fluconazole | Descriptor: | 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sagatova, A, Keniya, M.V, Wilson, R, Monk, B.C, Tyndall, J.D.A. | Deposit date: | 2015-04-20 | Release date: | 2016-03-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
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4GKH
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor 1-NA-PP1 | Descriptor: | 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Todorovic, N, Capretta, A, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-08-11 | Release date: | 2012-09-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.863 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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4N6W
| X-Ray Crystal Structure of Citrate-bound PhnZ | Descriptor: | CITRATE ANION, FE (III) ION, Predicted HD phosphohydrolase PhnZ | Authors: | Worsdorfer, B, Lingaraju, M, Yennawar, N.H, Boal, A.K, Krebs, C, Bollinger Jr, J.M, Pandelia, M.E. | Deposit date: | 2013-10-14 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases. Proc.Natl.Acad.Sci.USA, 110, 2013
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4G1P
| Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae | Descriptor: | CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ... | Authors: | Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S. | Deposit date: | 2012-07-11 | Release date: | 2013-07-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.547 Å) | Cite: | Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae To be published
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4YA0
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