4O6Z

Crystal structure of serine hydroxymethyltransferase with covalently bound PLP Schiff-base from Plasmodium falciparum

Summary for 4O6Z

Entry DOI	10.2210/pdb4o6z/pdb
Descriptor	Serine hydroxymethyltransferase, PYRIDOXAL-5'-PHOSPHATE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	alpha/beta protein, transferase, methyltransferase activity, cytosol
Biological source	Plasmodium falciparum
Total number of polymer chains	4
Total formula weight	217302.49
Authors	Chitnumsub, P.,Jaruwat, A.,Leartsakulpanich, U. (deposition date: 2013-12-24, release date: 2014-06-11, Last modification date: 2023-11-08)
Primary citation	Chitnumsub, P.,Ittarat, W.,Jaruwat, A.,Noytanom, K.,Amornwatcharapong, W.,Pornthanakasem, W.,Chaiyen, P.,Yuthavong, Y.,Leartsakulpanich, U. The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities. Acta Crystallogr.,Sect.D, 70:1517-1527, 2014 Cited by PubMed: 24914963 DOI: 10.1107/S1399004714005598 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.98 Å)

Structure validation