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4Z1T

MIF in complex with 4-[(4-oxo-2-thioxo-1,3-thiazolan-3-yl)methyl]benzonitrile

Summary for 4Z1T
Entry DOI10.2210/pdb4z1t/pdb
Related4Z15 4Z1U
DescriptorMacrophage migration inhibitory factor, ISOPROPYL ALCOHOL, SULFATE ION, ... (4 entities in total)
Functional Keywordscovalent inhibitor, protein surface modification, isomerase-isomerase inhibitor complex, isomerase/isomerase inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total formula weight38092.28
Authors
Cho, T.Y. (deposition date: 2015-03-27, release date: 2016-09-28, Last modification date: 2023-09-27)
Primary citationSingh, A.K.,Pantouris, G.,Borosch, S.,Rojanasthien, S.,Cho, T.Y.
Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors.
J. Cell. Mol. Med., 21:142-153, 2017
Cited by
PubMed: 27619729
DOI: 10.1111/jcmm.12949
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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