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2Q4G
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BU of 2q4g by Molmil
Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I
Descriptor: CITRIC ACID, Ribonuclease inhibitor, Ribonuclease pancreatic
Authors:Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2007-05-31
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein.
J.Mol.Biol., 368, 2007
3L28
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BU of 3l28 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant
Descriptor: CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
6JE3
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BU of 6je3 by Molmil
Crystal structure of Nme2Cas9 in complex with sgRNA and target DNA (AGGCCC PAM) with 5 nt overhang
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, non-target DNA strand, ...
Authors:Sun, W, Yang, J, Cheng, Z, Liu, C, Wang, K, Huang, X, Wang, Y.
Deposit date:2019-02-03
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.931 Å)
Cite:Structures of Neisseria meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States.
Mol.Cell, 76, 2019
3L8U
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BU of 3l8u by Molmil
Crystal structure of SMU.1707c, a putative rRNA methyltransferase from streptococcus mutans UA159
Descriptor: Putative rRNA methylase
Authors:Gao, X.-Z, Wang, K.-T, Su, X.-D.
Deposit date:2010-01-04
Release date:2011-01-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of SMU.1707c, a putative rRNA methyltransferase from streptococcus mutans UA159
To be published
1LMV
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BU of 1lmv by Molmil
Solution structure of the unmodified U2 snRNA-intron branch site helix from S. cerevisiae
Descriptor: 5'-R(*GP*GP*UP*GP*UP*AP*GP*UP*A)-3', 5'-R(*UP*AP*CP*UP*AP*AP*CP*AP*CP*C)-3'
Authors:Newby, M.I, Greenbaum, N.L.
Deposit date:2002-05-02
Release date:2002-11-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Sculpting of the Spliceosomal Branch Site Recognition Motif by a Conserved Pseudouridine
Nat.Struct.Biol., 9, 2002
1LPW
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BU of 1lpw by Molmil
Solution structure of the yeast spliceosomal U2 snRNA-intron branch site helix featuring a conserved pseudouridine
Descriptor: 5'-R(*GP*GP*UP*GP*(PSU)P*AP*GP*UP*A)-3', 5'-R(*UP*AP*CP*UP*AP*AP*CP*AP*CP*C)-3'
Authors:Newby, M.I, Greenbaum, N.L.
Deposit date:2002-05-08
Release date:2002-11-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Sculpting of the Spliceosomal Branch Site Recognition Motif by a Conserved Pseudouridine
Nat.Struct.Biol., 12, 2002
2ESJ
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BU of 2esj by Molmil
Complex between Lividomycin A and the 16S-Rrna A Site
Descriptor: (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Westhof, E.
Deposit date:2005-10-26
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding
Nucleic Acids Res., 33, 2005
2FZ2
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BU of 2fz2 by Molmil
Structure of Turnip Yellow Mosaic Virus at 100 K
Descriptor: 5'-R(*CP*CP*C)-3', Coat protein
Authors:Larson, S.B, Lucas, R.W, McPherson, A.
Deposit date:2006-02-08
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The RNA of turnip yellow mosaic virus exhibits icosahedral order.
Virology, 334, 2005
1WFX
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BU of 1wfx by Molmil
Crystal Structure of APE0204 from Aeropyrum pernix
Descriptor: CHLORIDE ION, Probable RNA 2'-phosphotransferase, ZINC ION
Authors:Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-27
Release date:2004-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the RNA 2'-Phosphotransferase from Aeropyrum pernix K1
J.Mol.Biol., 348, 2005
5XBL
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BU of 5xbl by Molmil
Structure of nuclease in complex with associated protein
Descriptor: Associated protein, CRISPR-associated endonuclease Cas9/Csn1, RNA (98-MER)
Authors:Dong, D, Guo, M, Wang, S, Zhu, Y, Huang, Z.
Deposit date:2017-03-20
Release date:2017-06-14
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.052 Å)
Cite:Structural basis of CRISPR-SpyCas9 inhibition by an anti-CRISPR protein
Nature, 546, 2017
1J3L
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BU of 1j3l by Molmil
Structure of the RNA-processing inhibitor RraA from Thermus thermophilis
Descriptor: CHLORIDE ION, Demethylmenaquinone Methyltransferase, MAGNESIUM ION
Authors:Rehse, P.H, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-02-04
Release date:2004-02-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the RNA-processing inhibitor RraA from Thermus thermophilis.
Acta Crystallogr.,Sect.D, 60, 2004
7VA6
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BU of 7va6 by Molmil
PaOrn Oligoribonuclease D11A mutant with RNA GU complex structure
Descriptor: IMIDAZOLE, Oligoribonuclease, RNA (5'-R(P*GP*U)-3')
Authors:Zhang, J, Zhang, Q, Bartlam, M.
Deposit date:2021-08-27
Release date:2022-09-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:PaOrn Oligoribonuclease D11A mutant with RNA GU complex structure
To Be Published
2WHO
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BU of 2who by Molmil
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR
Descriptor: 2-(3-bromophenyl)-6-[(2-hydroxyethyl)amino]-1h-benzo[de]isoquinoline-1,3(2h)-dione, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Di Marco, S.
Deposit date:2009-05-05
Release date:2009-08-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification and biological evaluation of a series of 1H-benzo[de]isoquinoline-1,3(2H)-diones as hepatitis C virus NS5B polymerase inhibitors.
J. Med. Chem., 52, 2009
2HXY
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BU of 2hxy by Molmil
Crystal structure of human apo-eIF4AIII
Descriptor: Probable ATP-dependent RNA helicase DDX48
Authors:Johansen, J.S, Andersen, G.R.
Deposit date:2006-08-04
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
1U20
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BU of 1u20 by Molmil
Crystal Structure of Xenopus laevis nudix hydrolase nuclear SnoRNA decapping Protein X29
Descriptor: GLYCEROL, U8 snoRNA-binding protein X29
Authors:Scarsdale, J.N, Peculis, B.A, Wright, H.T.
Deposit date:2004-07-16
Release date:2005-07-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of Xenopus laevis nudix hydrolase nuclear SnoRNA decapping Protein X29
TO BE PUBLISHED
4NRM
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BU of 4nrm by Molmil
Crystal structure of human ALKBH5 in complex with citrate and acetate
Descriptor: ACETATE ION, CITRATE ANION, RNA demethylase ALKBH5
Authors:Feng, C, Chen, Z, Liu, Y.
Deposit date:2013-11-27
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
7JV7
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BU of 7jv7 by Molmil
Crystal Structure of the yeast RNA Pol II CTD kinase CTDK-1 complex
Descriptor: CITRATE ANION, CTD kinase subunit alpha, CTD kinase subunit beta, ...
Authors:Xie, Y, Ren, Y.
Deposit date:2020-08-20
Release date:2021-01-27
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.850553 Å)
Cite:Structure and activation mechanism of the yeast RNA Pol II CTD kinase CTDK-1 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MEU
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BU of 7meu by Molmil
A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders
Descriptor: (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E
Authors:Papadopoulos, E.
Deposit date:2021-04-07
Release date:2021-04-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
Eur.J.Med.Chem., 219, 2021
4NRP
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BU of 4nrp by Molmil
Crystal structure of human ALKBH5 in complex with N-oxalylglycine
Descriptor: MANGANESE (II) ION, N-OXALYLGLYCINE, RNA demethylase ALKBH5
Authors:Feng, C, Chen, Z, Liu, Y.
Deposit date:2013-11-27
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
4O7X
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BU of 4o7x by Molmil
Crystal structure of human ALKBH5 in complex with Mn2+
Descriptor: MANGANESE (II) ION, RNA demethylase ALKBH5
Authors:Feng, C, Chen, Z, Liu, Y.
Deposit date:2013-12-26
Release date:2014-03-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition
J.Biol.Chem., 289, 2014
2PO0
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BU of 2po0 by Molmil
Crystal structure of the P. abyssi exosome RNase PH ring complexed with ADP in double conformation
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Probable exosome complex exonuclease 1, ...
Authors:Navarro, M.V.A.S, Guimaraes, B.G.
Deposit date:2007-04-25
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into the mechanism of progressive RNA degradation by the archaeal exosome.
J.Biol.Chem., 283, 2008
2PO2
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BU of 2po2 by Molmil
Crystal structure of the P. abyssi exosome RNase PH ring complexed with CDP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-5'-DIPHOSPHATE, Probable exosome complex exonuclease 1, ...
Authors:Navarro, M.V.A.S, Guimaraes, B.G.
Deposit date:2007-04-25
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Insights into the mechanism of progressive RNA degradation by the archaeal exosome.
J.Biol.Chem., 283, 2008
433D
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BU of 433d by Molmil
CRYSTAL STRUCTURE OF A 14 BASE PAIR RNA DUPLEX WITH NONSYMMETRICAL TANDEM G.U WOBBLE BASE PAIRS
Descriptor: 5'-R(*GP*GP*UP*AP*UP*UP*GP*CP*GP*GP*UP*AP*CP*C)-3'
Authors:Trikha, J, Filman, D.J, Hogle, J.M.
Deposit date:1998-10-22
Release date:1998-12-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a 14 bp RNA duplex with non-symmetrical tandem GxU wobble base pairs.
Nucleic Acids Res., 27, 1999
2PNZ
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BU of 2pnz by Molmil
Crystal structure of the P. abyssi exosome RNase PH ring complexed with UDP and GMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-MONOPHOSPHATE, Probable exosome complex exonuclease 1, ...
Authors:Navarro, M.V.A.S, Guimaraes, B.G.
Deposit date:2007-04-25
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Insights into the mechanism of progressive RNA degradation by the archaeal exosome.
J.Biol.Chem., 283, 2008
5X2G
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BU of 5x2g by Molmil
Crystal structure of Campylobacter jejuni Cas9 in complex with sgRNA and target DNA (AGAAACC PAM)
Descriptor: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9, Non-target DNA strand, ...
Authors:Yamada, M, Watanabe, Y, Hirano, H, Nakane, T, Ishitani, R, Nishimasu, H, Nureki, O.
Deposit date:2017-01-31
Release date:2017-03-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems
Mol. Cell, 65, 2017

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