2Q4G
Ensemble refinement of the protein crystal structure of human ribonuclease inhibitor complexed with ribonuclease I
Summary for 2Q4G
Entry DOI | 10.2210/pdb2q4g/pdb |
Descriptor | Ribonuclease pancreatic, Ribonuclease inhibitor, CITRIC ACID, ... (4 entities in total) |
Functional Keywords | ensemble refinement, refinement methodology development, ribonuclease-inhibitor complex, leucine-rich repeat, enzyme-inhibitor complex, structural genomics, protein structure initiative, psi, center for eukaryotic structural genomics, cesg, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P07998 Cytoplasm: P13489 |
Total number of polymer chains | 4 |
Total formula weight | 129686.03 |
Authors | Levin, E.J.,Kondrashov, D.A.,Wesenberg, G.E.,Phillips Jr., G.N.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2007-05-31, release date: 2007-06-19, Last modification date: 2023-08-30) |
Primary citation | Johnson, R.J.,McCoy, J.G.,Bingman, C.A.,Phillips Jr., G.N.,Raines, R.T. Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. J.Mol.Biol., 368:434-449, 2007 Cited by PubMed: 17350650DOI: 10.1016/j.jmb.2007.02.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.954 Å) |
Structure validation
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