6V03
| ELIC-propylammonium complex in POPC-only nanodiscs | Descriptor: | 3-AMINOPROPANE, Gamma-aminobutyric-acid receptor subunit beta-1 | Authors: | Grosman, C, Kumar, P. | Deposit date: | 2019-11-18 | Release date: | 2020-01-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc.Natl.Acad.Sci.USA, 117, 2020
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6UW8
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3DS0
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6V0B
| Unliganded ELIC in POPC-only nanodiscs. | Descriptor: | Gamma-aminobutyric-acid receptor subunit beta-1 | Authors: | Grosman, C, Kumar, P. | Deposit date: | 2019-11-18 | Release date: | 2020-01-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc.Natl.Acad.Sci.USA, 117, 2020
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6HQC
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7N29
| Structure of NAD kinase | Descriptor: | NAD kinase 2, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Du, J, Estrella, M.A, Jeffrey, P.D, Korennykh, A.V. | Deposit date: | 2021-05-28 | Release date: | 2022-05-04 | Last modified: | 2022-06-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc.Natl.Acad.Sci.USA, 119, 2022
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3S86
| Crystal Structure of TM0159 with bound IMP | Descriptor: | INOSINIC ACID, Nucleoside-triphosphatase, SULFATE ION | Authors: | Sommerhalter, M, Smith, C, Awwad, K, Desai, A. | Deposit date: | 2011-05-27 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and functional characterization of a noncanonical nucleoside triphosphate pyrophosphatase from Thermotoga maritima. Acta Crystallogr.,Sect.D, 69, 2013
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7N9H
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1BW9
| PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE | Descriptor: | 1,2-ETHANEDIOL, 3-PHENYLPYRUVIC ACID, ISOPROPYL ALCOHOL, ... | Authors: | Vanhooke, J.L, Thoden, J.B, Brunhuber, N.M.W, Blanchard, J.L, Holden, H.M. | Deposit date: | 1998-10-01 | Release date: | 1999-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Phenylalanine dehydrogenase from Rhodococcus sp. M4: high-resolution X-ray analyses of inhibitory ternary complexes reveal key features in the oxidative deamination mechanism. Biochemistry, 38, 1999
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6V7P
| Crystal structure of SUMO1 in complex with PIAS-SIM2 | Descriptor: | Protein PIAS, Small ubiquitin-related modifier 1 | Authors: | Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Sakaguchi, K, Omichinski, J.G. | Deposit date: | 2019-12-09 | Release date: | 2020-04-08 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins. Structure, 28, 2020
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7ODC
| CRYSTAL STRUCTURE ORNITHINE DECARBOXYLASE FROM MOUSE, TRUNCATED 37 RESIDUES FROM THE C-TERMINUS, TO 1.6 ANGSTROM RESOLUTION | Descriptor: | PROTEIN (ORNITHINE DECARBOXYLASE), PYRIDOXAL-5'-PHOSPHATE | Authors: | Kern, A.D, Oliveira, M.A, Coffino, P, Hackert, M.L. | Deposit date: | 1999-03-03 | Release date: | 1999-10-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases. Structure Fold.Des., 7, 1999
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6VJA
| Structure of CD20 in complex with rituximab Fab | Descriptor: | B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, Rituximab Fab heavy chain, ... | Authors: | Rohou, A, Croll, T.I. | Deposit date: | 2020-01-15 | Release date: | 2020-02-26 | Last modified: | 2020-03-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab. Science, 367, 2020
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8R1C
| SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SD1-2 fab heavy chain, SD1-2 fab light chain, ... | Authors: | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | Deposit date: | 2023-11-01 | Release date: | 2024-03-13 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86. Nat Commun, 15, 2024
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3D5E
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1B3O
| TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE | Descriptor: | 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), ... | Authors: | Colby, T.D, Vanderveen, K, Strickler, M.D, Goldstein, B.M. | Deposit date: | 1998-12-14 | Release date: | 1999-04-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proc.Natl.Acad.Sci.USA, 96, 1999
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7NUR
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5GSQ
| Crystal structure of IgG Fc with a homogeneous glycoform and Antibody-Dependent Cellular Cytotoxicity | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Chen, C.-L, Hsu, J.-C, Lin, C.-W, Wu, C.-Y, Wong, C.-H, Ma, C. | Deposit date: | 2016-08-17 | Release date: | 2017-06-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of a Homogeneous IgG-Fc Glycoform with the N-Glycan Designed to Maximize the Antibody Dependent Cellular Cytotoxicity ACS Chem. Biol., 12, 2017
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5G1S
| Open conformation of Francisella tularensis ClpP at 1.7 A | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | Authors: | Diaz-Saez, L, Pankov, G, Hunter, W.N. | Deposit date: | 2016-03-30 | Release date: | 2016-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Open and compressed conformations of Francisella tularensis ClpP. Proteins, 85, 2017
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3DTJ
| HIV-1 capsid C-terminal domain mutant (E187A) | Descriptor: | HIV-1 capsid protein | Authors: | Igonet, S, Vaney, M.C, Rey, F.A. | Deposit date: | 2008-07-15 | Release date: | 2008-09-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283, 2008
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6VVU
| Anti-Tryptase fab E104.v1 bound to tryptase | Descriptor: | CALCIUM ION, Fab E104.v1 heavy chain, Fab E104.v1 light chain, ... | Authors: | Ultsch, M, Koerber, J.T. | Deposit date: | 2020-02-18 | Release date: | 2020-12-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Bivalent antibody pliers inhibit beta-tryptase by an allosteric mechanism dependent on the IgG hinge. Nat Commun, 11, 2020
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1B4W
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1B70
| PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINE | Descriptor: | MAGNESIUM ION, PHENYLALANINE, PHENYLALANYL-TRNA SYNTHETASE | Authors: | Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G. | Deposit date: | 1999-01-26 | Release date: | 2000-02-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue J.Mol.Biol., 287, 1999
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1K8C
| Crystal structure of dimeric xylose reductase in complex with NADP(H) | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, xylose reductase | Authors: | Kavanagh, K.L, Klimacek, M, Nidetzky, B, Wilson, D.K. | Deposit date: | 2001-10-23 | Release date: | 2002-07-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of apo and holo forms of xylose reductase, a dimeric aldo-keto reductase from Candida tenuis. Biochemistry, 41, 2002
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1C2O
| ELECTROPHORUS ELECTRICUS ACETYLCHOLINESTERASE | Descriptor: | ACETYLCHOLINESTERASE | Authors: | Bourne, Y, Marchot, P. | Deposit date: | 1999-07-26 | Release date: | 2000-01-19 | Last modified: | 2021-06-02 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Conformational flexibility of the acetylcholinesterase tetramer suggested by x-ray crystallography. J.Biol.Chem., 274, 1999
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6I4U
| Crystal structure of the disease-causing G426E mutant of the human dihydrolipoamide dehydrogenase | Descriptor: | Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Szabo, E, Wilk, P, Hubert, A, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. | Deposit date: | 2018-11-10 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants. Hum.Mol.Genet., 28, 2019
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