6VJA

Structure of CD20 in complex with rituximab Fab

Summary for 6VJA

• Entry DOI: 10.2210/pdb6vja/pdb
• EMDB information: 21212
• Descriptor: B-lymphocyte antigen CD20, Rituximab Fab heavy chain, Rituximab Fab light chain, ... (4 entities in total)
• Functional Keywords: ms4a1, cd20, human, rituximab, therapeutic, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 159186.26

Authors

Rohou, A.,Croll, T.I. (deposition date: 2020-01-15, release date: 2020-02-26, Last modification date: 2020-03-25)

• Primary citation: Rouge, L.,Chiang, N.,Steffek, M.,Kugel, C.,Croll, T.I.,Tam, C.,Estevez, A.,Arthur, C.P.,Koth, C.M.,Ciferri, C.,Kraft, E.,Payandeh, J.,Nakamura, G.,Koerber, J.T.,Rohou, A.; Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab.; Science, 367:1224-1230, 2020; PubMed: 32079680; DOI: 10.1126/science.aaz9356

Experimental method

ELECTRON MICROSCOPY (3.3 Å)