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6VJA

Structure of CD20 in complex with rituximab Fab

Functional Information from GO Data
ChainGOidnamespacecontents
C0016020cellular_componentmembrane
D0016020cellular_componentmembrane
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue Y01 C 1001
ChainResidue
CMET71
CPHE154
CHIS158
DY01401

site_idAC2
Number of Residues2
Detailsbinding site for residue Y01 C 1002
ChainResidue
CILE96
CLEU122

site_idAC3
Number of Residues3
Detailsbinding site for residue Y01 C 1003
ChainResidue
CLYS142
CSER188
DY01403

site_idAC4
Number of Residues1
Detailsbinding site for residue Y01 D 401
ChainResidue
CY011001

site_idAC5
Number of Residues3
Detailsbinding site for residue Y01 D 402
ChainResidue
DMET93
DILE96
DLEU122

site_idAC6
Number of Residues4
Detailsbinding site for residue Y01 D 403
ChainResidue
CY011003
DMET71
DPHE154
DHIS158

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
HTYR194-HIS200
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues162
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
CILE57-ALA78
CTRP85-GLU105
CSER121-ILE141
CLEU189-ALA209
DILE57-ALA78
DTRP85-GLU105
DSER121-ILE141
DLEU189-ALA209

site_idSWS_FT_FI2
Number of Residues102
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
CPRO79-VAL84
CLYS142-SER188
DPRO79-VAL84
DLYS142-SER188

site_idSWS_FT_FI3
Number of Residues202
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
CLYS106-ASN120
CGLY210-PRO297
DLYS106-ASN120
DGLY210-PRO297

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P19437
ChainResidueDetails
CSER225
DSER225

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P19437
ChainResidueDetails
CTHR239
DTHR239

site_idSWS_FT_FI6
Number of Residues2
DetailsLIPID: S-palmitoyl cysteine => ECO:0000305|PubMed:22615937
ChainResidueDetails
CCYS111
DCYS111

site_idSWS_FT_FI7
Number of Residues2
DetailsLIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:22615937
ChainResidueDetails
CCYS220
DCYS220

226707

PDB entries from 2024-10-30

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