6VJA
Structure of CD20 in complex with rituximab Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (C, D) | B-lymphocyte antigen CD20 | polymer | 278 | 31320.8 | 2 | UniProt (P11836) Pfam (PF04103) | Homo sapiens (Human) | B-lymphocyte surface antigen B1,Bp35,Leukocyte surface antigen Leu-16,Membrane-spanning 4-domains subfamily A member 1 |
| 2 | C, D (H, I) | Rituximab Fab heavy chain | polymer | 224 | 23733.5 | 2 | Homo sapiens | ||
| 3 | E, F (L, M) | Rituximab Fab light chain | polymer | 213 | 23078.6 | 2 | Homo sapiens | ||
| 4 | G, H, I, J, K... (C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
C, D: 41 - 297 (UniProt: P11836)
| PDB | External Database | Details |
|---|---|---|
| Met 38 | - | initiating methionine |
| Gly 39 | - | expression tag |
| Ser 40 | - | expression tag |
| Gly 298 | - | expression tag |
| Asn 299 | - | expression tag |
| Ser 300 | - | expression tag |
| Glu 301 | - | expression tag |
| Asn 302 | - | expression tag |
| Leu 303 | - | expression tag |
| Tyr 304 | - | expression tag |
| Phe 305 | - | expression tag |
| Gln 306 | - | expression tag |
| Gly 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
| His 310 | - | expression tag |
| His 311 | - | expression tag |
| His 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
| His 315 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 156265.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2920.4 | |
| All* | Total formula weight | 159186.3 |
