8R1C

SD1-2 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein

Summary for 8R1C

• Entry DOI: 10.2210/pdb8r1c/pdb
• Related: 8CIN
• EMDB information: 18807
• Descriptor: Spike glycoprotein,Fibritin, SD1-2 fab heavy chain, SD1-2 fab light chain, ... (4 entities in total)
• Functional Keywords: sars-cov-2, spike, glycoprotein, coronavirus, antibody, fab, sd1 domain, therapeutic, complex, neutralisingm convalescent sera, viral protein, immune system, sd1-2, ba.2.12.1, omicron variant, virus, ba.2.86
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 9
• Total formula weight: 509054.14

Authors

Duyvesteyn, H.M.E.,Ren, J.,Stuart, D.I. (deposition date: 2023-11-01, release date: 2024-03-13, Last modification date: 2024-04-10)

• Primary citation: Zhou, D.,Supasa, P.,Liu, C.,Dijokaite-Guraliuc, A.,Duyvesteyn, H.M.E.,Selvaraj, M.,Mentzer, A.J.,Das, R.,Dejnirattisai, W.,Temperton, N.,Klenerman, P.,Dunachie, S.J.,Fry, E.E.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA.2.86.; Nat Commun, 15:2734-2734, 2024; PubMed: 38548763; DOI: 10.1038/s41467-024-46982-6

Experimental method

ELECTRON MICROSCOPY (2.2 Å)