1B3O

TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE

Summary for 1B3O

DescriptorPROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE, ... (5 entities in total)
Functional Keywordsdehydrogenase, impd, impdh, guanine nucleotide synthesis
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight113917.74
Authors
Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Goldstein, B.M. (deposition date: 1998-12-14, release date: 1999-04-12, Last modification date: 2011-07-13)
Primary citation
Colby, T.D.,Vanderveen, K.,Strickler, M.D.,Markham, G.D.,Goldstein, B.M.
Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Proc.Natl.Acad.Sci.USA, 96:3531-3536, 1999
PubMed: 10097070 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.96.7.3531
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.262385.1%5.9%2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report