4A1R
| The Structure of Serratia marcescens Lip, a membrane bound component of the Type VI Secretion System. | Descriptor: | 1,2-ETHANEDIOL, LIP, SODIUM ION | Authors: | Rao, V.A, Shepherd, S.M, English, G, Coulthurst, S.J, Hunter, W.N. | Deposit date: | 2011-09-19 | Release date: | 2011-10-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | The Structure of Serratia Marcescens Lip, a Membrane-Bound Component of the Type Vi Secretion System Acta Crystallogr.,Sect.F, 67, 2011
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7R58
| Crystal structure of the GPVI-glenzocimab complex | Descriptor: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | Authors: | Jandrot-Perrus, M, Lebozec, K, Rose, N, Welin, M, Billiald, P. | Deposit date: | 2022-02-10 | Release date: | 2022-11-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition. Blood Adv, 7, 2023
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5OP6
| Factor Inhibiting HIF (FIH) in complex with zinc and GSK128863 | Descriptor: | 2-[[1,3-dicyclohexyl-4-oxidanyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Leissing, T.M, Schofield, C.J, Clifton, I.J, Thinnes, C.C, Lu, X. | Deposit date: | 2017-08-09 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chem Sci, 8, 2017
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7R4S
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7R56
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1LYD
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2VOV
| An oxidized tryptophan facilitates copper-binding in Methylococcus capsulatus secreted protein MopE. The structure of wild-type MopE to 1.35AA | Descriptor: | CALCIUM ION, COPPER (II) ION, SURFACE-ASSOCIATED PROTEIN | Authors: | Helland, R, Fjellbirkeland, A, Karlsen, O.A, Ve, T, Lillehaug, J.R, Jensen, H.B. | Deposit date: | 2008-02-22 | Release date: | 2008-03-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope. J.Biol.Chem., 283, 2008
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7SFX
| 10A1 Fab in complex with CD99 peptide | Descriptor: | 10A1 Fab heavy chain, 10A1 Fab light chain, CD99 antigen peptide | Authors: | Romero, L.A, Hattori, T, Koide, S. | Deposit date: | 2021-10-04 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | High-valency Anti-CD99 Antibodies Toward the Treatment of T Cell Acute Lymphoblastic Leukemia. J.Mol.Biol., 434, 2021
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5OP8
| Factor Inhibiting HIF (FIH) in complex with zinc and Molidustat | Descriptor: | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)-1~{H}-pyrazol-3-one, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | Authors: | Leissing, T.M, Schofield, C.J, Clifton, I.J, Lu, X. | Deposit date: | 2017-08-09 | Release date: | 2017-10-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials. Chem Sci, 8, 2017
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3ZH4
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7RW8
| AP2 bound to heparin in the closed conformation | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Baker, R.W, Hollopeter, G, Partlow, E.A. | Deposit date: | 2021-08-19 | Release date: | 2022-03-30 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization. Nat.Struct.Mol.Biol., 29, 2022
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7S3R
| NMR Solution Structure of hGal(1-12)KK, a solubility-tagged truncation of the human neuropeptide galanin | Descriptor: | Galanin | Authors: | Kraichely, K.N, Mendoza, E.A, Parnham, S, Giuliano, M.W. | Deposit date: | 2021-09-08 | Release date: | 2022-05-25 | Last modified: | 2022-07-06 | Method: | SOLUTION NMR | Cite: | Minimal Increments of Hydrophobic Collapse within the N-Terminus of the Neuropeptide Galanin. Biochemistry, 61, 2022
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7SAP
| The CTI-homolog pacifastin | Descriptor: | GLYCEROL, Serine protease inhibitor I/II-like Protein | Authors: | Gewe, M.M, Strong, R.K. | Deposit date: | 2021-09-23 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14, 2022
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5TC1
| In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2 | Descriptor: | Capsid protein, Maturation protein, phage MS2 genome | Authors: | Dai, X.H, Li, Z.H, Lai, M, Shu, S, Du, Y.S, Zhou, Z.H, Sun, R. | Deposit date: | 2016-09-13 | Release date: | 2016-12-07 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. Nature, 541, 2017
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3ZH8
| A novel small molecule aPKC inhibitor | Descriptor: | (2S)-3-phenyl-N~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kjaer, S, Purkiss, A.G, Kostelecky, B, Knowles, P.P, Soriano, E, Murray-Rust, J, McDonald, N.Q. | Deposit date: | 2012-12-20 | Release date: | 2013-02-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.739 Å) | Cite: | Adenosine-Binding Motif Mimicry and Cellular Effects of a Thieno[2,3-D]Pyrimidine-Based Chemical Inhibitor of Atypical Protein Kinase C Isozymes. Biochem.J., 451, 2013
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2XVA
| Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin | Descriptor: | SINEFUNGIN, TELLURITE RESISTANCE PROTEIN TEHB, ZINC ION | Authors: | Choudhury, H.G, Cameron, A.D, Iwata, S, Beis, K. | Deposit date: | 2010-10-25 | Release date: | 2011-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Mechanism of the Chalcogen Detoxifying Protein Tehb from Escherichia Coli. Biochem.J., 435, 2011
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5W0W
| Crystal structure of Protein Phosphatase 2A bound to TIPRL | Descriptor: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... | Authors: | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | Deposit date: | 2017-06-01 | Release date: | 2018-01-17 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Methylation-regulated decommissioning of multimeric PP2A complexes. Nat Commun, 8, 2017
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5WAM
| Structure of BamE from Neisseria gonorrhoeae | Descriptor: | Outer membrane protein assembly factor BamE, ZINC ION | Authors: | Korotkov, K.V, Buchanan, S.K, Noinaj, N. | Deposit date: | 2017-06-26 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural and functional insights into the role of BamD and BamE within the beta-barrel assembly machinery in Neisseria gonorrhoeae. J. Biol. Chem., 293, 2018
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9EQG
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9C57
| Reconstituted P400 Subcomplex of the human TIP60 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | Deposit date: | 2024-06-05 | Release date: | 2024-08-21 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.75 Å) | Cite: | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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9IMA
| Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab | Descriptor: | CHOLESTEROL, G-protein coupled receptor family C group 5 member D, Talquetamab Fab (anti-GPRC5D) Heavy chain, ... | Authors: | Jeong, J, Shin, J, Park, J, Cho, Y. | Deposit date: | 2024-07-02 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma. J.Mol.Biol., 436, 2024
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9FAA
| Cryo-EM structure of cardiac collagen-associated amyloid AL59 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | Authors: | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | Deposit date: | 2024-05-10 | Release date: | 2024-07-17 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis. Nat Commun, 15, 2024
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9J9A
| Staphylococcus aureus exfoliative toxin D | Descriptor: | SULFATE ION, Serine protease, beta-D-glucopyranose | Authors: | Tonozuka, T. | Deposit date: | 2024-08-22 | Release date: | 2024-09-11 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of exfoliative toxin D from Staphylococcus aureus. Biochem.Biophys.Res.Commun., 733, 2024
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9C8U
| Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | Descriptor: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | Authors: | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | Deposit date: | 2024-06-13 | Release date: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min To Be Published
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9FAC
| Additional cryo-EM structure of cardiac amyloid AL59 - mixed polymorph | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | Authors: | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | Deposit date: | 2024-05-10 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis. Nat Commun, 15, 2024
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