9IMA
Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab
Summary for 9IMA
Entry DOI | 10.2210/pdb9ima/pdb |
EMDB information | 60686 |
Descriptor | Talquetamab Fab (anti-GPRC5D) Heavy chain, Talquetamab Fab (anti-GPRC5D) Light chain, G-protein coupled receptor family C group 5 member D, ... (4 entities in total) |
Functional Keywords | talquetamab, class c gpcr, multiple myeloma, bispecific antibody, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 4 |
Total formula weight | 130203.43 |
Authors | |
Primary citation | Jeong, J.,Park, J.,Young Mo, G.,Shin, J.,Cho, Y. Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma. J.Mol.Biol., 436:168748-168748, 2024 Cited by PubMed: 39181182DOI: 10.1016/j.jmb.2024.168748 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.65 Å) |
Structure validation
Download full validation report