7SAP

The CTI-homolog pacifastin

Summary for 7SAP

Entry DOI	10.2210/pdb7sap/pdb
Descriptor	Serine protease inhibitor I/II-like Protein, GLYCEROL (3 entities in total)
Functional Keywords	cti-homolog, pacifastin, cdp, cystine-dense peptides, toxin
Biological source	Tribolium castaneum
Total number of polymer chains	2
Total formula weight	7384.30
Authors	Gewe, M.M.,Strong, R.K. (deposition date: 2021-09-23, release date: 2022-08-03, Last modification date: 2023-10-18)
Primary citation	Crook, Z.R.,Girard, E.J.,Sevilla, G.P.,Brusniak, M.Y.,Rupert, P.B.,Friend, D.J.,Gewe, M.M.,Clarke, M.,Lin, I.,Ruff, R.,Pakiam, F.,Phi, T.D.,Bandaranayake, A.,Correnti, C.E.,Mhyre, A.J.,Nairn, N.W.,Strong, R.K.,Olson, J.M. Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager. Sci Transl Med, 14:eabn0402-eabn0402, 2022 Cited by PubMed: 35584229 DOI: 10.1126/scitranslmed.abn0402 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation