6ZMT
| SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-03 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZMO
| SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-03 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZME
| SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-02 | Release date: | 2020-08-12 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZMI
| SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-02 | Release date: | 2020-08-19 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZLW
| SARS-CoV-2 Nsp1 bound to the human 40S ribosomal subunit | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-01 | Release date: | 2020-07-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6ZM7
| SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-01 | Release date: | 2020-07-29 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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6XIR
| Cryo-EM Structure of K63 Ubiquitinated Yeast Translocating Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XIQ
| Cryo-EM Structure of K63R Ubiquitin Mutant Ribosome under Oxidative Stress | Descriptor: | 18S ribosomal RNA, 35S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Zhou, Y, Bartesaghi, A, Silva, G.M. | Deposit date: | 2020-06-21 | Release date: | 2020-08-26 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. Proc.Natl.Acad.Sci.USA, 117, 2020
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6XII
| Escherichia coli transcription-translation complex B (TTC-B) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-06-20 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XIJ
| Escherichia coli transcription-translation complex A (TTC-A) containing an 24 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-06-20 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XHY
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. | Deposit date: | 2020-06-19 | Release date: | 2020-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021
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6XHV
| Crystal structure of the A2058-dimethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.40A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. | Deposit date: | 2020-06-19 | Release date: | 2020-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021
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6XHW
| Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.50A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. | Deposit date: | 2020-06-19 | Release date: | 2020-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021
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6XHX
| Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Svetlov, M.S, Syroegin, E.A, Aleksandrova, E.V, Atkinson, G.C, Gregory, S.T, Mankin, A.S, Polikanov, Y.S. | Deposit date: | 2020-06-19 | Release date: | 2020-12-23 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance. Nat.Chem.Biol., 17, 2021
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6XGF
| Escherichia coli transcription-translation complex B (TTC-B) containing an 30 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-06-17 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XDR
| Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | Deposit date: | 2020-06-11 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XE0
| Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) | Descriptor: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. | Deposit date: | 2020-06-11 | Release date: | 2020-07-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
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6XDQ
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-06-11 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6ZCE
| Structure of a yeast ABCE1-bound 43S pre-initiation complex | Descriptor: | 18S ribosomal RNA (1719-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-06-10 | Release date: | 2020-10-07 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
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6X9Q
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 27 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-06-03 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XA1
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6X7K
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-05-30 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6X6T
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B1 (TTC-B1) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-05-29 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6X7F
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B2 (TTC-B2) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | Deposit date: | 2020-05-29 | Release date: | 2020-09-02 | Last modified: | 2020-09-23 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of transcription-translation coupling. Science, 369, 2020
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6Z6M
| Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | Deposit date: | 2020-05-28 | Release date: | 2020-07-29 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. Plos Biol., 18, 2020
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