Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1

This is a large structure.

Summary for 6Z6M

EMDB information11099
Descriptor28S rRNA, 5S rRNA, 5.8S rRNA, ... (86 entities in total)
Functional Keywordsribosome, hibernation
Biological sourceHomo sapiens (Human)
Total number of polymer chains84
Total molecular weight4023533.23
Primary citation
Wells, J.N.,Buschauer, R.,Mackens-Kiani, T.,Best, K.,Kratzat, H.,Berninghausen, O.,Becker, T.,Gilbert, W.,Cheng, J.,Beckmann, R.
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18:e3000780-e3000780, 2020
PubMed: 32687489 (PDB entries with the same primary citation)
DOI: 10.1371/journal.pbio.3000780
MImport into Mendeley
Experimental method

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 0.2% 0.8% 0.49MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-08-12