6ZM7
SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-EBP1 ribosome complex
This is a non-PDB format compatible entry.
Summary for 6ZM7
Entry DOI | 10.2210/pdb6zm7/pdb |
EMDB information | 11276 11288 |
Descriptor | 28S ribosomal RNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (88 entities in total) |
Functional Keywords | translational inhibition, sars-cov-2, immune evasion, human ribosome, viral protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 86 |
Total formula weight | 3976249.26 |
Authors | Thoms, M.,Buschauer, R.,Ameismeier, M.,Denk, T.,Kratzat, H.,Mackens-Kiani, T.,Cheng, J.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2020-07-01, release date: 2020-07-29, Last modification date: 2024-05-01) |
Primary citation | Thoms, M.,Buschauer, R.,Ameismeier, M.,Koepke, L.,Denk, T.,Hirschenberger, M.,Kratzat, H.,Hayn, M.,Mackens-Kiani, T.,Cheng, J.,Straub, J.H.,Sturzel, C.M.,Frohlich, T.,Berninghausen, O.,Becker, T.,Kirchhoff, F.,Sparrer, K.M.J.,Beckmann, R. Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369:1249-1255, 2020 Cited by PubMed: 32680882DOI: 10.1126/science.abc8665 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
Download full validation report