6ZME

SARS-CoV-2 Nsp1 bound to the human CCDC124-80S-eERF1 ribosome complex

This is a non-PDB format compatible entry.
Summary for 6ZME
EMDB information11276 11289
Descriptor28S ribosomal RNA, 60S ribosomal protein L7a, 60S ribosomal protein L9, ... (92 entities in total)
Functional Keywordstranslational inhibition, sars-cov-2, immune evasion, human ribosome, viral protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains88
Total formula weight4093877.71
Authors
Thoms, M.,Buschauer, R.,Ameismeier, M.,Denk, T.,Kratzat, H.,Mackens-Kiani, T.,Cheng, J.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2020-07-02, release date: 2020-08-12, Last modification date: 2020-09-16)
Primary citationAmeismeier, M.,Becker, T.,Beckmann, R.,Berninghausen, O.,Buschauer, R.,Cheng, J.,Denk, T.,Frohlich, T.,Hayn, M.,Hirschenberger, M.,Kirchhoff, F.,Koepke, L.,Kratzat, H.,Mackens-Kiani, T.,Sparrer, K.M.J.,Straub, J.H.,Sturzel, C.M.,Thoms, M.
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369:1249-1255, 2020
PubMed: 32680882
DOI: 110.1126/science.abc8665
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3 Å)
Structure validation
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PDB entries from 2021-06-16