PDB: 10891 resultsInfo pagesStatus searchChemie searchBIRD

---

6KIX	Cryo-EM structure of human MLL1-NCP complex, binding mode1 Descriptor: DNA (145-MER), GLUTAMINE, Histone H2A, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIZ	Cryo-EM structure of human MLL1-NCP complex, binding mode2 Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
6KIV	Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom) Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ... Authors: Huang, J, Xue, H, Yao, T. Deposit date: 2019-07-20 Release date: 2019-09-11 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structural basis of nucleosome recognition and modification by MLL methyltransferases. Nature, 573, 2019
5OY3	The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ... Authors: Jones, S.E, Olsen, L, Gajhede, M. Deposit date: 2017-09-07 Release date: 2017-09-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.136 Å) Cite: Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57, 2018
8DS8	Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein Authors: Song, J.K, Lu, J.W. Deposit date: 2022-07-21 Release date: 2023-08-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.84 Å) Cite: TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature, 623, 2023
6XPQ	Human antibody D1 H1-17/H3-14 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) Descriptor: Hemagglutinin, antibody D1 H1-17/H3-14 light chain, antibody D1 H1-17/H3-14 heavy chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2020-07-08 Release date: 2021-05-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (4.2 Å) Cite: A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
1F5U	SOLUTION STRUCTURE OF THE KISSING DIMER OF H3 GACG STEM-LOOP IN THE 5'-END DIMERIZATION SIGNAL OF MOLONEY MURINE LEUKEMIA VIRUS GENOMIC RNA Descriptor: RNA (5'-R(*GP*GP*UP*GP*GP*GP*AP*GP*AP*CP*GP*UP*CP*CP*CP*AP*CP*C)-3') Authors: Kim, C.-H, Tinoco Jr, I. Deposit date: 2000-06-16 Release date: 2000-08-21 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: A retroviral RNA kissing complex containing only two G.C base pairs. Proc.Natl.Acad.Sci.USA, 97, 2000
7E9C	Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ... Authors: Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. Deposit date: 2021-03-04 Release date: 2022-09-07 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published
7E9F	Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ... Authors: Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. Deposit date: 2021-03-04 Release date: 2022-09-07 Method: ELECTRON MICROSCOPY (4 Å) Cite: Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1 To Be Published
2OS2	Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys36 Descriptor: JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... Authors: Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2007-02-05 Release date: 2007-03-13 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
2OQ6	Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys9 Descriptor: JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... Authors: Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2007-01-31 Release date: 2007-03-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
2OX0	Crystal structure of JMJD2A complexed with histone H3 peptide dimethylated at Lys9 Descriptor: CHLORIDE ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ... Authors: Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2007-02-19 Release date: 2007-03-13 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
7ZEZ	Trimolecular complex Cyp33-RRMdelta alpha : MLL1-PHD3 : H3K4me3 Descriptor: Histone H3, Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, MLL cleavage product N320, ... Authors: Blatter, M, Allain, F, Meylan, C. Deposit date: 2022-03-31 Release date: 2022-04-13 Last modified: 2023-05-03 Method: SOLUTION NMR Cite: RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
6VYP	Crystal structure of the LSD1/CoREST histone demethylase bound to its nucleosome substrate Descriptor: DNA (191-MER), FLAVIN-ADENINE DINUCLEOTIDE, Histone H2A type 1, ... Authors: Kim, S, Zhu, J, Eek, P, Yennawar, N, Song, T. Deposit date: 2020-02-27 Release date: 2020-05-27 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (4.99 Å) Cite: Crystal Structure of the LSD1/CoREST Histone Demethylase Bound to Its Nucleosome Substrate. Mol.Cell, 78, 2020
3AN2	The structure of the centromeric nucleosome containing CENP-A Descriptor: 147 mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Tachiwana, H, Kagawa, W, Shiga, T, Saito, K, Osakabe, A, Hayashi-Takanaka, Y, Park, S.-Y, Kimura, H, Kurumizaka, H. Deposit date: 2010-08-27 Release date: 2011-07-20 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystal structure of the human centromeric nucleosome containing CENP-A Nature, 476, 2011
7X6L	Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12 Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of the antibody 12 fab Authors: Cong, Y, Liu, C.X. Deposit date: 2022-03-07 Release date: 2022-03-23 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus. Nat Commun, 13, 2022
6Z2A	Structure of Clr4 mutant - F256A/F310A/F427A bound to SAH Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific, MAGNESIUM ION, ... Authors: Stirpe, A, Schalch, T. Deposit date: 2020-05-15 Release date: 2021-05-26 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.456 Å) Cite: SUV39 SET domains mediate crosstalk of heterochromatic histone marks. Elife, 10, 2021
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH Descriptor: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE Authors: Du, J, Patel, D.J. Deposit date: 2012-06-27 Release date: 2012-10-17 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
7D20	Cryo-EM structure of SET8-CENP-A-nucleosome complex Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... Authors: Ho, C.-H, Takizawa, Y, Kobayashi, W, Arimura, Y, Kurumizaka, H. Deposit date: 2020-09-15 Release date: 2021-02-10 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural basis of nucleosomal histone H4 lysine 20 methylation by SET8 methyltransferase. Life Sci Alliance, 4, 2021
8HQY	Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom Descriptor: DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... Authors: Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. Deposit date: 2022-12-14 Release date: 2023-09-27 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
2HIO	HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN Descriptor: PROTEIN (HISTONE H2A), PROTEIN (HISTONE H2B), PROTEIN (HISTONE H3), ... Authors: Arents, G, Moudrianakis, E.N. Deposit date: 1999-06-15 Release date: 2000-01-12 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc.Natl.Acad.Sci.USA, 88, 1991
6R1T	Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome Descriptor: DNA (147-MER), HISTONE H2A, Histone H2A, ... Authors: Marabelli, C, Pilotto, S, Chittori, S, Subramaniam, S, Mattevi, A. Deposit date: 2019-03-15 Release date: 2019-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex. Cell Rep, 27, 2019
8HR1	Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... Authors: Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L. Deposit date: 2022-12-14 Release date: 2023-09-13 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.02 Å) Cite: Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes. Nat.Struct.Mol.Biol., 31, 2024
6TEM	CENP-A nucleosome core particle with 145 base pairs of the Widom 601 sequence by cryo-EM Descriptor: Histone H2A, Histone H2B 1.1, Histone H3-like centromeric protein A, ... Authors: Boopathi, R, Danev, R, Petosa, C, Bednar, J. Deposit date: 2019-11-12 Release date: 2020-04-08 Last modified: 2020-06-10 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Phase-plate cryo-EM structure of the Widom 601 CENP-A nucleosome core particle reveals differential flexibility of the DNA ends. Nucleic Acids Res., 48, 2020
1HIO	HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN, ALPHA CARBONS ONLY Descriptor: HISTONE H2A, HISTONE H2B, HISTONE H3, ... Authors: Arents, G, Moudrianakis, E.N. Deposit date: 1991-09-19 Release date: 1998-11-25 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc.Natl.Acad.Sci.USA, 88, 1991

<20212223242526272829303132333435>