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6R1T

Structure of LSD2/NPAC-linker/nucleosome core particle complex: Class 1, free nuclesome

Summary for 6R1T
Entry DOI10.2210/pdb6r1t/pdb
EMDB information4704
DescriptorHistone H3, HISTONE H2A, Histone H2A, ... (6 entities in total)
Functional Keywordshistone demethylation, chromatin reader, flavoenzyme, epigenetics, evolution of protein function, molecular recognition., gene regulation
Biological sourceXenopus laevis (African clawed frog)
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Total number of polymer chains10
Total formula weight179944.89
Authors
Marabelli, C.,Pilotto, S.,Chittori, S.,Subramaniam, S.,Mattevi, A. (deposition date: 2019-03-15, release date: 2019-04-24)
Primary citationMarabelli, C.,Marrocco, B.,Pilotto, S.,Chittori, S.,Picaud, S.,Marchese, S.,Ciossani, G.,Forneris, F.,Filippakopoulos, P.,Schoehn, G.,Rhodes, D.,Subramaniam, S.,Mattevi, A.
A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
Cell Rep, 27:387-399.e7, 2019
Cited by
PubMed: 30970244
DOI: 10.1016/j.celrep.2019.03.061
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.7 Å)
Structure validation

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