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8HR1

Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom

Summary for 8HR1
Entry DOI10.2210/pdb8hr1/pdb
EMDB information34956
DescriptorHistone H3, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
Functional Keywordsssx1, unmodified nucleosome, synovial sarcoma, ssbaf, reader protein, structural protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains11
Total formula weight178041.42
Authors
Zebin, T.,Ai, H.S.,Ziyu, X.,Man, P.,Liu, L. (deposition date: 2022-12-14, release date: 2023-09-13, Last modification date: 2024-03-06)
Primary citationTong, Z.,Ai, H.,Xu, Z.,He, K.,Chu, G.C.,Shi, Q.,Deng, Z.,Xue, Q.,Sun, M.,Du, Y.,Liang, L.,Li, J.B.,Pan, M.,Liu, L.
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31:300-310, 2024
Cited by
PubMed: 38177667
DOI: 10.1038/s41594-023-01141-1
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.02 Å)
Structure validation

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