8GT1
| Crystal structure of human cardiac alpha actin A108G mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GSW
| Crystal structure of human cardiac alpha actin A108G mutant (AMPPNP state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT2
| Crystal structure of human cardiac alpha actin P109A mutant (AMPPNP state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, Actin, alpha cardiac muscle 1, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT5
| Crystal structure of human cardiac alpha actin Q137A mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8GT3
| Crystal structure of human cardiac alpha actin P109A mutant (ADP-Pi state) in complex with fragmin F1 domain | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Iwasa, M, Oda, T, Takeda, S. | Deposit date: | 2022-09-07 | Release date: | 2023-03-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Mutagenic analysis of actin reveals the mechanism of His161 flipping that triggers ATP hydrolysis. Front Cell Dev Biol, 11, 2023
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8EFI
| Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in the rigor form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | Deposit date: | 2022-09-08 | Release date: | 2022-11-23 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. J.Gen.Physiol., 155, 2023
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8EFH
| Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in complex with ADP-Mg2+ | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | Deposit date: | 2022-09-08 | Release date: | 2023-01-11 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. J.Gen.Physiol., 155, 2023
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8ENC
| Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Doran, M.H, Lehman, W, Rynkiewicz, M.J. | Deposit date: | 2022-09-29 | Release date: | 2022-11-23 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. J.Gen.Physiol., 155, 2023
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8ESC
| Structure of the Yeast NuA4 Histone Acetyltransferase Complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | Authors: | Patel, A.B, Zukin, S.A, Nogales, E. | Deposit date: | 2022-10-13 | Release date: | 2022-11-16 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and flexibility of the yeast NuA4 histone acetyltransferase complex. Elife, 11, 2022
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8ETS
| Class1 of the INO80-Hexasome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | Deposit date: | 2022-10-17 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8ETU
| Class2 of the INO80-Hexasome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | Deposit date: | 2022-10-17 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8ETW
| Class3 of INO80-Hexasome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | Deposit date: | 2022-10-17 | Release date: | 2023-07-19 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8EUF
| Class2 of the INO80-Nucleosome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | Deposit date: | 2022-10-18 | Release date: | 2023-07-12 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8EU9
| Class1 of the INO80-Nucleosome complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G. | Deposit date: | 2022-10-18 | Release date: | 2023-07-12 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8BJJ
| ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | Deposit date: | 2022-11-04 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BJH
| chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | Deposit date: | 2022-11-04 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BJI
| chimera of ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo fused to a proline-Rich-Domain (PRD) and profilin, bound to ADP-Mg-actin and a sulfate ion | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | Deposit date: | 2022-11-04 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BO1
| ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AZIDE ION, ... | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | Deposit date: | 2022-11-14 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8BR0
| ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin | Descriptor: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Texeira-Nuns, M, Retailleau, P, Renault, L. | Deposit date: | 2022-11-22 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.218 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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8F8P
| Cryo-EM structure of F-actin in the ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8Q
| Cryo-EM structure of the CapZ-capped barbed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8R
| Cryo-EM structure of the free barbed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8T
| Cryo-EM structure of the Tropomodulin-capped pointed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8F8S
| Cryo-EM structure of the free pointed end of F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Carman, P.J, Barrie, K.R, Dominguez, R. | Deposit date: | 2022-11-22 | Release date: | 2023-06-07 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (2.84 Å) | Cite: | Structures of the free and capped ends of the actin filament. Science, 380, 2023
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8BR1
| ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Teixeira-Nunes, M, Renault, L, Retailleau, P. | Deposit date: | 2022-11-22 | Release date: | 2023-09-20 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.044 Å) | Cite: | Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
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