8ENC

Helical reconstruction of the human cardiac actin-tropomyosin-myosin loop 4 7G mutant complex

Summary for 8ENC

• Entry DOI: 10.2210/pdb8enc/pdb
• EMDB information: 28270
• Descriptor: Myosin-7, Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ... (5 entities in total)
• Functional Keywords: actin, tropomyosin, myosin, cardiac, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 501040.56

Authors

Doran, M.H.,Lehman, W.,Rynkiewicz, M.J. (deposition date: 2022-09-29, release date: 2022-11-23, Last modification date: 2022-12-14)

• Primary citation: Doran, M.H.,Rynkiewicz, M.J.,Pavadai, E.,Bodt, S.M.L.,Rasicci, D.,Moore, J.R.,Yengo, C.M.,Bullitt, E.,Lehman, W.; Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation.; J.Gen.Physiol., 155:-, 2023; PubMed: 36459134; DOI: 10.1085/jgp.202213274

Experimental method

ELECTRON MICROSCOPY (3.6 Å)