8BO1

ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to Latrunculin-B-ATP-Mg-actin, and 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE and 2 Mg ions

Summary for 8BO1

Entry DOI	10.2210/pdb8bo1/pdb
Related	7PQJ 7QC4 8BJH 8BJI 8BJJ
Descriptor	Actin, alpha skeletal muscle, intermediate form, CHLORIDE ION, Putative Adenylate cyclase, ... (11 entities in total)
Functional Keywords	bacterial nucleotidyl cyclase toxin, activated complex, toxin
Biological source	Vibrio nigripulchritudo More
Total number of polymer chains	4
Total formula weight	180204.48
Authors	Teixeira-Nunes, M.,Renault, L.,Retailleau, P. (deposition date: 2022-11-14, release date: 2023-09-20, Last modification date: 2023-10-04)
Primary citation	Teixeira-Nunes, M.,Retailleau, P.,Raoux-Barbot, D.,Comisso, M.,Missinou, A.A.,Velours, C.,Plancqueel, S.,Ladant, D.,Mechold, U.,Renault, L. Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19:e1011654-e1011654, 2023 Cited by PubMed: 37747912 DOI: 10.1371/journal.ppat.1011654 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.501 Å)

Structure validation