8BJJ

ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion

Summary for 8BJJ

Entry DOI	10.2210/pdb8bjj/pdb
Related	7PJ0 7PK7 7PQJ
Descriptor	Actin, alpha skeletal muscle, intermediate form, TETRAETHYLENE GLYCOL, GLYCEROL, ... (12 entities in total)
Functional Keywords	bacterial nucleotidyl cyclase toxin, activated complex, toxin
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	104960.00
Authors	Teixeira-Nunes, M.,Renault, L.,Retailleau, P. (deposition date: 2022-11-04, release date: 2023-09-20, Last modification date: 2023-10-04)
Primary citation	Teixeira-Nunes, M.,Retailleau, P.,Raoux-Barbot, D.,Comisso, M.,Missinou, A.A.,Velours, C.,Plancqueel, S.,Ladant, D.,Mechold, U.,Renault, L. Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19:e1011654-e1011654, 2023 Cited by PubMed: 37747912 DOI: 10.1371/journal.ppat.1011654 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.699 Å)

Structure validation