8BJJ
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin, alpha skeletal muscle, intermediate form | polymer | 375 | 41862.6 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | |
| 2 | B (C) | Profilin-1 | polymer | 139 | 14940.0 | 1 | UniProt (P07737) Pfam (PF00235) | Homo sapiens (human) | Epididymis tissue protein Li 184a,Profilin I |
| 3 | C (B) | Putative Adenylate cyclase | polymer | 413 | 46247.5 | 1 | UniProt (A0A6N3LUE9) Pfam (PF03497) UniProt (by SIFTS) (A0A9P1NJI6) | Vibrio nigripulchritudo | MARTX toxin |
| 4 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | LATRUNCULIN B | non-polymer | 395.5 | 1 | Chemie (LAB) | |||
| 7 | G, N (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 8 | H, K, L, M (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 9 | I, J (C) | HYDROGEN PEROXIDE | non-polymer | 34.0 | 2 | Chemie (PEO) | |||
| 10 | O (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 11 | P (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 12 | Q, R, S (A, C, B) | water | water | 18.0 | 722 | Chemie (HOH) |
Sequence modifications
B: 455 - 863 (UniProt: A0A6N3LUE9)
| PDB | External Database | Details |
|---|---|---|
| Gly 451 | - | expression tag |
| Pro 452 | - | expression tag |
| Gly 453 | - | expression tag |
| Ser 454 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103050.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1909.9 | |
| All* | Total formula weight | 104960.0 |
