8BJJ
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Actin, alpha skeletal muscle, intermediate form | polymer | 375 | 41862.6 | 1 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | |
| 2 | B (C) | Profilin-1 | polymer | 139 | 14940.0 | 1 | UniProt (P07737) Pfam (PF00235) | Homo sapiens (human) | Epididymis tissue protein Li 184a,Profilin I |
| 3 | C (B) | Putative Adenylate cyclase | polymer | 413 | 46247.5 | 1 | UniProt (A0A6N3LUE9) UniProt (by SIFTS) (A0A9P1NJI6) | Vibrio nigripulchritudo | MARTX toxin |
| 4 | D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | LATRUNCULIN B | non-polymer | 395.5 | 1 | Chemie (LAB) PubChem (16760044) PubChem (20054954) PubChem (3892) PubChem (22832299) PubChem (23424960) PubChem (23863831) PubChem (25215545) PubChem (72940) PubChem (57370013) PubChem (59169653) PubChem (59431496) PubChem (67441199) PubChem (67441200) PubChem (56928133) PubChem (88895461) PubChem (90912141) PubChem (5352046) PubChem (5353712) PubChem (98044135) PubChem (92209860) PubChem (6436219) PubChem (98044136) PubChem (98044137) PubChem (10000783) PubChem (14504487) PubChem (162928966) PubChem (129388766) PubChem (129388767) PubChem (146159701) PubChem (154825202) PubChem (162928961) PubChem (162928962) PubChem (162928963) PubChem (162928964) PubChem (162928965) PubChem (162928967) PubChem (163195209) PubChem (168317464) PubChem (171039486) | |||
| 7 | G, N (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) PubChem (3777159) | |||
| 8 | H, K, L, M (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 9 | I, J (C) | HYDROGEN PEROXIDE | non-polymer | 34.0 | 2 | Chemie (PEO) PubChem (784) | |||
| 10 | O (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 11 | P (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 12 | Q, R, S (A, C, B) | water | water | 18.0 | 722 | Chemie (HOH) |
Sequence modifications
B: 455 - 863 (UniProt: A0A6N3LUE9)
| PDB | External Database | Details |
|---|---|---|
| Gly 451 | - | expression tag |
| Pro 452 | - | expression tag |
| Gly 453 | - | expression tag |
| Ser 454 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 103050.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1909.9 | |
| All* | Total formula weight | 104960.0 |
