8EFH

Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in complex with ADP-Mg2+

Summary for 8EFH

• Entry DOI: 10.2210/pdb8efh/pdb
• EMDB information: 28082
• Descriptor: beta-cardiac myosin II, Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain, ... (5 entities in total)
• Functional Keywords: actin, tropomyosin, myosin, cardiac, motor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 377718.43

Authors

Doran, M.H.,Lehman, W.,Rynkiewicz, M.J. (deposition date: 2022-09-08, release date: 2023-01-11, Last modification date: 2023-01-25)

• Primary citation: Doran, M.H.,Rynkiewicz, M.J.,Rassici, D.,Bodt, S.M.L.,Barry, M.E.,Bullitt, E.,Yengo, C.M.,Moore, J.R.,Lehman, W.; Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin.; J.Gen.Physiol., 155:-, 2023; PubMed: 36633586; DOI: 10.1085/jgp.202213267

Experimental method

ELECTRON MICROSCOPY (3.3 Å)