8EFH
Helical reconstruction of the human cardiac actin-tropomyosin-myosin complex in complex with ADP-Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | beta-cardiac myosin II | polymer | 865 | 99157.7 | 1 | UniProt (P12883) Pfam (PF02736) Pfam (PF00063) | Homo sapiens (human) | Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta |
| 2 | B, C, D, E, F (F, B, C, D, E) | Actin, alpha cardiac muscle 1 | polymer | 377 | 42064.9 | 5 | UniProt (B6VNT8) Pfam (PF00022) UniProt (by SIFTS) (P68137) | Sus scrofa (pig) | Cardiac muscle alpha actin 1 |
| 3 | G, H (O, P) | Tropomyosin alpha-1 chain | polymer | 284 | 32763.6 | 2 | UniProt (P09493) Pfam (PF00261) | Homo sapiens (human) | Alpha-tropomyosin,Tropomyosin-1 |
| 4 | I, L, N, P, R... (A, F, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 5 | J, K, M, O, Q... (A, F, B, C, D...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) |
Sequence modifications
A: 1 - 842 (UniProt: P12883)
| PDB | External Database | Details |
|---|---|---|
| Gly 843 | - | expression tag |
| Leu 844 | - | expression tag |
| Asn 845 | - | expression tag |
| Asp 846 | - | expression tag |
| Ile 847 | - | expression tag |
| Phe 848 | - | expression tag |
| Glu 849 | - | expression tag |
| Ala 850 | - | expression tag |
| Gln 851 | - | expression tag |
| Lys 852 | - | expression tag |
| Ile 853 | - | expression tag |
| Glu 854 | - | expression tag |
| Trp 855 | - | expression tag |
| His 856 | - | expression tag |
| Glu 857 | - | expression tag |
| Asp 858 | - | expression tag |
| Tyr 859 | - | expression tag |
| Lys 860 | - | expression tag |
| Asp 861 | - | expression tag |
| Asp 862 | - | expression tag |
| Asp 863 | - | expression tag |
| Asp 864 | - | expression tag |
| Lys 865 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 375009.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2709.0 | |
| All* | Total formula weight | 377718.4 |
