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6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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BU of 6olg by Molmil
Human ribosome nascent chain complex stalled by a drug-like small molecule (CDH1_RNC with PP tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6Q8Y
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BU of 6q8y by Molmil
Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2018-12-16
Release date:2019-03-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
6H25
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BU of 6h25 by Molmil
Human nuclear RNA exosome EXO-10-MPP6 complex
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Gerlach, P, Schuller, J.M, Falk, S, Basquin, J, Conti, E.
Deposit date:2018-07-13
Release date:2018-08-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Distinct and evolutionary conserved structural features of the human nuclear exosome complex.
Elife, 7, 2018
6HCJ
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BU of 6hcj by Molmil
Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-15
Release date:2018-10-17
Last modified:2018-11-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
7A01
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BU of 7a01 by Molmil
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ...
Authors:Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-08-05
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
6HCF
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BU of 6hcf by Molmil
Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
Authors:Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S.
Deposit date:2018-08-14
Release date:2018-10-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72, 2018
5A22
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BU of 5a22 by Molmil
Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy
Descriptor: VESICULAR STOMATITIS VIRUS L POLYMERASE, ZINC ION
Authors:Liang, B, Li, Z, Jenni, S, Rameh, A.A, Morin, B.M, Grant, T, Grigorieff, N, Harrison, S.C, Whelan, S.P.J.
Deposit date:2015-05-06
Release date:2015-08-19
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the L Protein of Vesicular Stomatitis Virus from Electron Cryomicroscopy.
Cell(Cambridge,Mass.), 162, 2015
6ZVK
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BU of 6zvk by Molmil
The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ...
Authors:Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-07-24
Release date:2020-12-23
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
6ZUO
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BU of 6zuo by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage)
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
Authors:Plassart, L, Shayan, R, Plisson-Chastang, C.
Deposit date:2020-07-23
Release date:2021-05-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
3E2B
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BU of 3e2b by Molmil
Crystal structure of Dynein Light chain LC8 in complex with a peptide derived from Swallow
Descriptor: ACETATE ION, Dynein light chain 1, cytoplasmic, ...
Authors:Benison, G, Barbar, E, Karplus, P.A.
Deposit date:2008-08-05
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The interplay of ligand binding and quaternary structure in the diverse interactions of dynein light chain LC8.
J.Mol.Biol., 384, 2008
4QQD
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BU of 4qqd by Molmil
Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule
Descriptor: 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, E3 ubiquitin-protein ligase UHRF1, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2014-08-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
6J9F
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BU of 6j9f by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with the bacteriophage protein P7
Descriptor: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6J9E
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BU of 6j9e by Molmil
Cryo-EM structure of Xanthomonos oryzae transcription elongation complex with NusA and the bacteriophage protein P7
Descriptor: 45L, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:You, L.L, Zhang, Y.
Deposit date:2019-01-22
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structural basis for transcription antitermination at bacterial intrinsic terminator.
Nat Commun, 10, 2019
6MTB
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BU of 6mtb by Molmil
Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6MTC
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BU of 6mtc by Molmil
Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S.
Deposit date:2018-10-19
Release date:2018-11-21
Last modified:2019-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of translationally inactive mammalian ribosomes.
Elife, 7, 2018
6FSZ
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BU of 6fsz by Molmil
Structure of the nuclear RNA exosome
Descriptor: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ...
Authors:Schuller, J.M, Falk, S, Conti, E.
Deposit date:2018-02-20
Release date:2018-03-21
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the nuclear exosome captured on a maturing preribosome.
Science, 360, 2018
6PB5
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BU of 6pb5 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
8V7G
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BU of 8v7g by Molmil
Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2023-12-04
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+
To Be Published
6QSN
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BU of 6qsn by Molmil
Crystal structure of Yellow fever virus polymerase NS5A
Descriptor: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Boura, E, Dubankova, A.
Deposit date:2019-02-21
Release date:2019-10-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:Structure of the yellow fever NS5 protein reveals conserved drug targets shared among flaviviruses.
Antiviral Res., 169, 2019
4QWB
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BU of 4qwb by Molmil
CRYSTAL STRUCTURE of DPO4 LINKER REGION P236A MUTANT WITH AN INCOMING D-dCDP
Descriptor: ACETATE ION, CALCIUM ION, DEOXYCYTIDINE DIPHOSPHATE, ...
Authors:Vyas, R, Suo, Z.
Deposit date:2014-07-16
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase.
Nucleic Acids Res., 42, 2014
6R9B
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BU of 6r9b by Molmil
Cryo-EM structure of bacterial RNAP with a DNA mimic protein Ocr from T7 phage
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Ye, F.Z, Zhang, X.D.
Deposit date:2019-04-03
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7
Elife, 2020
6ZV6
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BU of 6zv6 by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Plassart, L, Shayan, R, Plisson-Chastang, C.
Deposit date:2020-07-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
8V7B
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BU of 8v7b by Molmil
Human DNA polymerase eta-DNA-dT primer araCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: 4-amino-1-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2023-12-04
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human DNA polymerase eta-DNA-dT primer araCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion
To Be Published
8V7D
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BU of 8v7d by Molmil
Human DNA polymerase eta-DNA-dT primer rCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion
Descriptor: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), ...
Authors:Chang, C, Gao, Y.
Deposit date:2023-12-04
Release date:2024-05-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Human DNA polymerase eta-DNA-dT primer rCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion
To Be Published

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