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PDB: 8 results

7Z52
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BU of 7z52 by Molmil
Human NEXT dimer - focused reconstruction of the single MTR4
Descriptor: Exosome RNA helicase MTR4, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), ...
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-07
Release date:2022-06-22
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
7Z4Y
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BU of 7z4y by Molmil
Human NEXT dimer - overall reconstruction of the core complex
Descriptor: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-06
Release date:2022-06-22
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
7Z4Z
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BU of 7z4z by Molmil
Human NEXT dimer - focused reconstruction of the dimerization module
Descriptor: Exosome RNA helicase MTR4, Zinc finger CCHC domain-containing protein 8
Authors:Gerlach, P, Lingaraju, M, Salerno-Kochan, A, Bonneau, F, Basquin, J, Conti, E.
Deposit date:2022-03-06
Release date:2022-06-22
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
Mol.Cell, 82, 2022
6H25
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BU of 6h25 by Molmil
Human nuclear RNA exosome EXO-10-MPP6 complex
Descriptor: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ...
Authors:Gerlach, P, Schuller, J.M, Falk, S, Basquin, J, Conti, E.
Deposit date:2018-07-13
Release date:2018-08-15
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Distinct and evolutionary conserved structural features of the human nuclear exosome complex.
Elife, 7, 2018
6Z6B
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BU of 6z6b by Molmil
Structure of full-length La Crosse virus L protein (polymerase)
Descriptor: RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), ...
Authors:Cusack, S, Gerlach, P, Reguera, J.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.961 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6G
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BU of 6z6g by Molmil
Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage
Descriptor: 3'vRNA 1-16, 5'vRNA 1-10, 5'vRNA 9-16, ...
Authors:Arragain, B, Effantin, G, Gerlach, P, Reguera, J, Schoehn, G, Cusack, S, Malet, H.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
5AMR
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BU of 5amr by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' viral RNA
Descriptor: RNA, RNA POLYMERASE L
Authors:Reguera, J, Gerlach, P, Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell(Cambridge,Mass.), 161, 2015
5AMQ
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BU of 5amq by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' and 5' viral RNA
Descriptor: RNA, RNA POLYMERASE L
Authors:Reguera, J, Gerlach, P, Cusack, S.
Deposit date:2015-03-12
Release date:2015-06-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell, 161, 2015

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