6Z6B

Structure of full-length La Crosse virus L protein (polymerase)

This is a large structure.

Summary for 6Z6B

DescriptorRNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3'), RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3'), ... (5 entities in total)
Functional Keywordsrna-dependent rna polymerase, viral protein
Biological sourceBunyavirus La Crosse
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Total number of polymer chains8
Total molecular weight553770.84
Authors
Cusack, S.,Gerlach, P.,Reguera, J. (deposition date: 2020-05-28, release date: 2020-07-29)
Primary citation
Arragain, B.,Effantin, G.,Gerlach, P.,Reguera, J.,Schoehn, G.,Cusack, S.,Malet, H.
Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11:3590-3590, 2020
PubMed: 32681014 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-020-17349-4
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.961 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2933 1.0% 4.1% 15.4% 0.45MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
167518
PDB entries from 2020-08-12