6Z6B

Structure of full-length La Crosse virus L protein (polymerase)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, G (BBB, UUU)	RNA (5'-R(P*AP*GP*UP*AP*GP*UP*GP*UP*GP*C)-3')	polymer	10	3218.0	2		La Crosse orthobunyavirus
2	B, E (CCC, HHH)	RNA (5'-R(P*UP*UP*AP*GP*UP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3')	polymer	16	5044.0	2		La Crosse orthobunyavirus
3	C, H (DDD, XXX)	RNA (5'-R(*GP*CP*UP*AP*CP*UP*AP*A)-3')	polymer	8	2510.6	2		La Crosse orthobunyavirus
4	D, F (EEE, PPP)	RNA-directed RNA polymerase L	polymer	2285	266047.5	2	UniProt (A5HC98) Pfam (PF15518) Pfam (PF04196) Pfam (PF21561)	Bunyavirus La Crosse	Protein L,Large structural protein,Replicase,Transcriptase
5	I, J (EEE, PPP)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

EEE, PPP: 1 - 2263 (UniProt: A5HC98)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Asp -13	-	expression tag
Tyr -12	-	expression tag
Asp -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Thr -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	553640.0
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	553770.8

*Water molecules are not included.