6Z6B

Structure of full-length La Crosse virus L protein (polymerase)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
EEE	0000166	molecular_function	nucleotide binding
EEE	0001172	biological_process	RNA-templated transcription
EEE	0003723	molecular_function	RNA binding
EEE	0003824	molecular_function	catalytic activity
EEE	0003968	molecular_function	RNA-dependent RNA polymerase activity
EEE	0006351	biological_process	DNA-templated transcription
EEE	0008152	biological_process	metabolic process
EEE	0016740	molecular_function	transferase activity
EEE	0016779	molecular_function	nucleotidyltransferase activity
EEE	0016787	molecular_function	hydrolase activity
EEE	0019079	biological_process	viral genome replication
EEE	0034062	molecular_function	5'-3' RNA polymerase activity
EEE	0039694	biological_process	viral RNA genome replication
EEE	0044165	cellular_component	host cell endoplasmic reticulum
EEE	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
EEE	0044177	cellular_component	host cell Golgi apparatus
EEE	0044423	cellular_component	virion component
EEE	0046872	molecular_function	metal ion binding
PPP	0000166	molecular_function	nucleotide binding
PPP	0001172	biological_process	RNA-templated transcription
PPP	0003723	molecular_function	RNA binding
PPP	0003824	molecular_function	catalytic activity
PPP	0003968	molecular_function	RNA-dependent RNA polymerase activity
PPP	0006351	biological_process	DNA-templated transcription
PPP	0008152	biological_process	metabolic process
PPP	0016740	molecular_function	transferase activity
PPP	0016779	molecular_function	nucleotidyltransferase activity
PPP	0016787	molecular_function	hydrolase activity
PPP	0019079	biological_process	viral genome replication
PPP	0034062	molecular_function	5'-3' RNA polymerase activity
PPP	0039694	biological_process	viral RNA genome replication
PPP	0044165	cellular_component	host cell endoplasmic reticulum
PPP	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
PPP	0044177	cellular_component	host cell Golgi apparatus
PPP	0044423	cellular_component	virion component
PPP	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. MGSiNLTITGYNRSItI

Chain	Residue	Details
EEE	MET1858-ILE1874

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:20862319

Chain	Residue	Details
EEE	HIS34
PPP	TYR93
EEE	ASP52
EEE	ASP79
EEE	ASP92
EEE	TYR93
PPP	HIS34
PPP	ASP52
PPP	ASP79
PPP	ASP92

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305|PubMed:26004069

Chain	Residue	Details
EEE	ASP1188
PPP	ASP1188

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site_id	SWS_FT_FI3
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:32681014, ECO:0007744|PDB:6Z6B

Chain	Residue	Details
EEE	CYS2064
EEE	HIS2169
EEE	ASP2178
EEE	HIS2182
PPP	CYS2064
PPP	HIS2169
PPP	ASP2178
PPP	HIS2182

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