6Z6B

Structure of full-length La Crosse virus L protein (polymerase)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
EEE	0000166	molecular_function	nucleotide binding
EEE	0001172	biological_process	RNA-templated transcription
EEE	0003723	molecular_function	RNA binding
EEE	0003824	molecular_function	catalytic activity
EEE	0003968	molecular_function	RNA-directed RNA polymerase activity
EEE	0006351	biological_process	DNA-templated transcription
EEE	0016740	molecular_function	transferase activity
EEE	0016779	molecular_function	nucleotidyltransferase activity
EEE	0016787	molecular_function	hydrolase activity
EEE	0019079	biological_process	viral genome replication
EEE	0034062	molecular_function	5'-3' RNA polymerase activity
EEE	0039694	biological_process	viral RNA genome replication
EEE	0044165	cellular_component	host cell endoplasmic reticulum
EEE	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
EEE	0044177	cellular_component	host cell Golgi apparatus
EEE	0044423	cellular_component	virion component
EEE	0046872	molecular_function	metal ion binding
PPP	0000166	molecular_function	nucleotide binding
PPP	0001172	biological_process	RNA-templated transcription
PPP	0003723	molecular_function	RNA binding
PPP	0003824	molecular_function	catalytic activity
PPP	0003968	molecular_function	RNA-directed RNA polymerase activity
PPP	0006351	biological_process	DNA-templated transcription
PPP	0016740	molecular_function	transferase activity
PPP	0016779	molecular_function	nucleotidyltransferase activity
PPP	0016787	molecular_function	hydrolase activity
PPP	0019079	biological_process	viral genome replication
PPP	0034062	molecular_function	5'-3' RNA polymerase activity
PPP	0039694	biological_process	viral RNA genome replication
PPP	0044165	cellular_component	host cell endoplasmic reticulum
PPP	0044172	cellular_component	host cell endoplasmic reticulum-Golgi intermediate compartment
PPP	0044177	cellular_component	host cell Golgi apparatus
PPP	0044423	cellular_component	virion component
PPP	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. MGSiNLTITGYNRSItI

Chain	Residue	Details
EEE	MET1858-ILE1874

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	376
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	368
Details	Region: {"description":"Endonuclease","evidences":[{"source":"PubMed","id":"32681014","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20862319","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26004069","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"32681014","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6Z6B","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---