7Z52

Human NEXT dimer - focused reconstruction of the single MTR4

Summary for 7Z52

• Entry DOI: 10.2210/pdb7z52/pdb
• Related: 7Z4Y
• EMDB information: 14510 14513
• Descriptor: Exosome RNA helicase MTR4, RNA (5'-R(P*UP*UP*UP*UP*U)-3'), Zinc finger CCHC domain-containing protein 8, ... (4 entities in total)
• Functional Keywords: helicase, atpase, rna degradation, exosome, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 199135.51

Authors

Gerlach, P.,Lingaraju, M.,Salerno-Kochan, A.,Bonneau, F.,Basquin, J.,Conti, E. (deposition date: 2022-03-07, release date: 2022-06-22, Last modification date: 2022-07-20)

• Primary citation: Gerlach, P.,Garland, W.,Lingaraju, M.,Salerno-Kochan, A.,Bonneau, F.,Basquin, J.,Jensen, T.H.,Conti, E.; Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.; Mol.Cell, 82:2505-, 2022; PubMed: 35688157; DOI: 10.1016/j.molcel.2022.04.011

Experimental method

ELECTRON MICROSCOPY (3.4 Å)