7Z52
Human NEXT dimer - focused reconstruction of the single MTR4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Exosome RNA helicase MTR4 | polymer | 1046 | 118322.1 | 1 | UniProt (P42285) Pfam (PF00270) Pfam (PF00271) Pfam (PF21408) Pfam (PF13234) Pfam (PF08148) | Homo sapiens (human) | ATP-dependent RNA helicase DOB1,ATP-dependent RNA helicase SKIV2L2,Superkiller viralicidic activity 2-like 2,TRAMP-like complex helicase |
| 2 | B (R) | RNA (5'-R(P*UP*UP*UP*UP*U)-3') | polymer | 5 | 1485.9 | 1 | synthetic construct | ||
| 3 | C (A) | Zinc finger CCHC domain-containing protein 8 | polymer | 709 | 78821.4 | 1 | UniProt (Q6NZY4) Pfam (PF00098) Pfam (PF04046) | Homo sapiens (human) | TRAMP-like complex RNA-binding factor ZCCHC8 |
| 4 | D (B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) |
Sequence modifications
B: 1 - 1042 (UniProt: P42285)
A: 1 - 707 (UniProt: Q6NZY4)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Arg -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 20 | Glu 20 | conflict |
| Gly 506 | Ala 506 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 198629.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 199135.5 |
