5T1A
 
 | | Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, ... | | Authors: | Zheng, Y, Qin, L, Ortiz Zacarias, N.V, de Vries, H, Han, G.W, Gustavsson, M, Dabros, M, Zhao, C, Cherney, R.J, Carter, P, Stamos, D, Abagyan, R, Cherezov, V, Stevens, R.C, IJzerman, A.P, Heitman, L.H, Tebben, A, Kufareva, I, Handel, T.M. | | Deposit date: | 2016-08-18 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.806 Å) | | Cite: | Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Nature, 540, 2016
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6L0L
 | | Hydra-1ubq de nova designed by Hydra based on ubiquitin | | Descriptor: | Hydra-1ubq | | Authors: | Ouyang, B. | | Deposit date: | 2019-09-26 | | Release date: | 2020-09-30 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Multiobjective heuristic algorithm for de novo protein design in a quantified continuous sequence space.
Comput Struct Biotechnol J, 19, 2021
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6MKM
 | | Crystallographic solvent mapping analysis of DMSO/Tris bound to APE1 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... | | Authors: | Georgiadis, M.M, He, H, Chen, Q. | | Deposit date: | 2018-09-25 | | Release date: | 2019-01-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.673 Å) | | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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6MK3
 | | Crystallographic solvent mapping analysis of DMSO bound to APE1 | | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase | | Authors: | Georgiadis, M.M, He, H, Chen, Q. | | Deposit date: | 2018-09-24 | | Release date: | 2019-01-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.478 Å) | | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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6MKO
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6MKK
 | | Crystallographic solvent mapping analysis of DMSO/Mg bound to APE1 | | Descriptor: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, DNA-(apurinic or apyrimidinic site) lyase, ... | | Authors: | Georgiadis, M.M, He, H, Chen, Q. | | Deposit date: | 2018-09-25 | | Release date: | 2019-01-30 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.442 Å) | | Cite: | Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
J. Med. Chem., 62, 2019
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1J46
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1J47
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1J4V
 | | CYANOVIRIN-N | | Descriptor: | CYANOVIRIN-N | | Authors: | Clore, G.M, Bewley, C.A. | | Deposit date: | 2001-11-21 | | Release date: | 2002-03-06 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings.
J.Magn.Reson., 154, 2002
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4V7L
 | | The structures of viomycin bound to the 70S ribosome. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Stanley, R.E, Blaha, G. | | Deposit date: | 2009-11-12 | | Release date: | 2014-07-09 | | Last modified: | 2018-07-11 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
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4V8C
 | | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin). | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | Authors: | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | | Deposit date: | 2011-12-07 | | Release date: | 2014-07-09 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
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4V87
 | | Crystal structure analysis of ribosomal decoding. | | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | Authors: | Demeshkina, N, Jenner, L, Yusupov, M, Yusupova, G. | | Deposit date: | 2011-09-20 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
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3K2K
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3K69
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3JSO
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3K9T
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3K6Q
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3JR1
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3JZ6
 | | Crystal structure of Mycobacterium smegmatis Branched Chain Aminotransferase in complex with pyridoxal-5'-phosphate at 1.9 angstrom. | | Descriptor: | Branched-chain amino acid aminotransferase, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Castell, A, Mille, C, Unge, T. | | Deposit date: | 2009-09-23 | | Release date: | 2010-05-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.
Acta Crystallogr.,Sect.D, 66, 2010
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3K29
 | | Structure of a putative YscO homolog CT670 from Chlamydia trachomatis | | Descriptor: | Putative uncharacterized protein | | Authors: | Lam, R, Singer, A, Skarina, T, Onopriyenko, O, Bochkarev, A, Brunzelle, J.S, Edwards, A.M, Anderson, W.F, Chirgadze, N.Y, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2009-09-29 | | Release date: | 2009-10-13 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and protein-protein interaction studies on Chlamydia trachomatis protein CT670 (YscO Homolog).
J.Bacteriol., 192, 2010
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3JQF
 | | Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 1,3,5-triazine-2,4,6-triamine (AX2) | | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 1,3,5-triazine-2,4,6-triamine, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | | Authors: | Tulloch, L.B, Hunter, W.N. | | Deposit date: | 2009-09-06 | | Release date: | 2009-12-08 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases.
J.Med.Chem., 53, 2010
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3K2V
 | | Structure of the CBS pair of a putative D-arabinose 5-phosphate isomerase from Klebsiella pneumoniae subsp. pneumoniae. | | Descriptor: | CYTIDINE 5'-MONOPHOSPHATE 3-DEOXY-BETA-D-GULO-OCT-2-ULO-PYRANOSONIC ACID, GLYCEROL, SULFATE ION, ... | | Authors: | Cuff, M.E, Volkart, L, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-09-30 | | Release date: | 2009-12-22 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of the CBS pair of a putative D-arabinose 5-phosphate isomerase from Klebsiella pneumoniae subsp. pneumoniae.
TO BE PUBLISHED
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3K8K
 | | Crystal structure of SusG | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Alpha-amylase, ... | | Authors: | Koropatkin, N.M, Smith, T.J. | | Deposit date: | 2009-10-14 | | Release date: | 2010-03-02 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | SusG: A Unique Cell-Membrane-Associated alpha-Amylase from a Prominent Human Gut Symbiont Targets Complex Starch Molecules.
Structure, 18, 2010
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3JWH
 | | Crystal structure analysis of the methyltransferase domain of bacterial-AvHen1-C | | Descriptor: | Hen1, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Huang, R.H, Chan, C.M, Zhou, C, Brunzelle, J.S. | | Deposit date: | 2009-09-18 | | Release date: | 2009-10-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3KAE
 | | Cdc27 N-terminus | | Descriptor: | CHLORIDE ION, GLYCEROL, Possible protein of nuclear scaffold, ... | | Authors: | Barford, D, Zhang, Z, Roe, S.M. | | Deposit date: | 2009-10-19 | | Release date: | 2010-03-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
J.Mol.Biol., 397, 2010
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