4PEI
| Dbr1 in complex with synthetic branched RNA analog | Descriptor: | GLYCEROL, NICKEL (II) ION, RNA (5'-R(*(G46)P*U)-3'), ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4PEG
| Dbr1 in complex with guanosine-5'-monophosphate | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4PEF
| Dbr1 in complex with sulfate | Descriptor: | GLYCEROL, MANGANESE (II) ION, RNA lariat debranching enzyme, ... | Authors: | Montemayor, E.J, Katolik, A, Clark, N.E, Taylor, A.B, Schuermann, J.P, Combs, D.J, Johnsson, R, Holloway, S.P, Stevens, S.W, Damha, M.J, Hart, P.J. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res., 42, 2014
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4Q7F
| 1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine. | Descriptor: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 5' nucleotidase family protein, MAGNESIUM ION, ... | Authors: | Minasov, G, Nocadello, S, Shuvalova, L, Dubrovska, I, Winsor, J, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-04-24 | Release date: | 2014-05-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | 1.98 Angstrom Crystal Structure of Putative 5'-Nucleotidase from Staphylococcus aureus in complex with Adenosine. TO BE PUBLISHED
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4MOV
| 1.45 A Resolution Crystal Structure of Protein Phosphatase 1 | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Choy, M.S, Peti, W, Page, R. | Deposit date: | 2013-09-12 | Release date: | 2014-03-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4503 Å) | Cite: | Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MOY
| Structure of a second nuclear PP1 Holoenzyme, crystal form 1 | Descriptor: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Choy, M.S, Hieke, M, Peti, W, Page, R. | Deposit date: | 2013-09-12 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1953 Å) | Cite: | Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MP0
| Structure of a second nuclear PP1 Holoenzyme, crystal form 2 | Descriptor: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | Authors: | Choy, M.S, Hieke, M, Peti, W, Page, R. | Deposit date: | 2013-09-12 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1003 Å) | Cite: | Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code. Proc.Natl.Acad.Sci.USA, 111, 2014
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4JA9
| Rat PP5 apo | Descriptor: | MAGNESIUM ION, Serine/threonine-protein phosphatase 5 | Authors: | Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K. | Deposit date: | 2013-02-18 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism. Biosci.Rep., 35, 2015
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4JA7
| Rat PP5 co-crystallized with P5SA-2 | Descriptor: | MAGNESIUM ION, Serine/threonine-protein phosphatase 5 | Authors: | Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K. | Deposit date: | 2013-02-18 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism. Biosci.Rep., 35, 2015
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3ZK4
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4O24
| DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | Descriptor: | (5~{Z})-5-[(4-hydroxyphenyl)methylidene]-3-(2-methylpropyl)-2-sulfanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ... | Authors: | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | Deposit date: | 2013-12-16 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
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4NZV
| DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | Descriptor: | Exonuclease, putative, MANGANESE (II) ION | Authors: | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | Deposit date: | 2013-12-12 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
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4O4K
| DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | Descriptor: | (5~{E})-2-azanylidene-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazolidin-4-one, Exonuclease, putative, ... | Authors: | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | Deposit date: | 2013-12-18 | Release date: | 2014-01-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
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4O43
| DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | Descriptor: | (5~{E})-3-[(2~{R})-butan-2-yl]-5-[(4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ... | Authors: | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | Deposit date: | 2013-12-18 | Release date: | 2014-01-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
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4O5G
| DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | Descriptor: | (5~{E})-5-[(4-aminophenyl)methylidene]-2-azanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ... | Authors: | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | Deposit date: | 2013-12-19 | Release date: | 2014-01-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
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4LAC
| Crystal Structure of Protein Phosphatase 2A (PP2A) and PP2A phosphatase activator (PTPA) complex with ATPgammaS | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Guo, F, Stanevich, V, Wlodarchak, N, Satyshur, K.A, Xing, Y. | Deposit date: | 2013-06-19 | Release date: | 2013-10-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone. Cell Res., 24, 2014
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4IL1
| Crystal Structure of the Rat Calcineurin | Descriptor: | CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ... | Authors: | Ye, Q, Faucher, F, Jia, Z. | Deposit date: | 2012-12-28 | Release date: | 2013-10-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of calcineurin activation by calmodulin. Cell Signal, 25, 2013
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4B2O
| Crystal structure of Bacillus subtilis YmdB, a global regulator of late adaptive responses. | Descriptor: | FE (II) ION, PHOSPHATE ION, YMDB PHOSPHODIESTERASE | Authors: | Newman, J.A, Diethmaier, C, Kovacs, A.T, Rodrigues, C, Kuipers, O.P, Stulke, J, Lewis, R.J. | Deposit date: | 2012-07-17 | Release date: | 2013-07-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis. J.Bacteriol., 196, 2014
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4I5N
| Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ... | Authors: | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | Deposit date: | 2012-11-28 | Release date: | 2013-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
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4I5L
| Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, MALONATE ION, ... | Authors: | Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y. | Deposit date: | 2012-11-28 | Release date: | 2013-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Res., 23, 2013
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4IYP
| structure of the nPP2Ac-alpha4 complex | Descriptor: | Immunoglobulin-binding protein 1, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | Authors: | Jiang, L, Stanevich, V, Satyshur, K.A, Xing, Y. | Deposit date: | 2013-01-29 | Release date: | 2013-04-17 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.797 Å) | Cite: | Structural basis of protein phosphatase 2A stable latency. Nat Commun, 4, 2013
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4J6O
| Crystal Structure of the Phosphatase Domain of C. thermocellum (Bacterial) PnkP | Descriptor: | CITRIC ACID, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Wang, L, Smith, P, Shuman, S. | Deposit date: | 2013-02-11 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system. Nucleic Acids Res., 41, 2013
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4F0Z
| Crystal Structure of Calcineurin in Complex with the Calcineurin-Inhibiting Domain of the African Swine Fever Virus Protein A238L | Descriptor: | Ankyrin repeat domain-containing protein A238L, CALCIUM ION, Calcineurin subunit B type 1, ... | Authors: | Grigoriu, S, Peti, W, Page, R. | Deposit date: | 2012-05-05 | Release date: | 2013-03-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. Plos Biol., 11, 2013
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4DHL
| Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment MO07123 | Descriptor: | 1,2-ETHANEDIOL, 2-(4-methylphenyl)-1,3-thiazole-4-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Feder, D, Clayton, D.J, Hussein, W.M, Schenk, G, McGeary, R, Guddat, L.W. | Deposit date: | 2012-01-29 | Release date: | 2012-12-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics. Chem.Biol.Drug Des., 80, 2012
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4H2B
| Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with Baicalin | Descriptor: | 5'-nucleotidase, 5,6-dihydroxy-4-oxo-2-phenyl-4H-chromen-7-yl beta-D-glucopyranosiduronic acid, CALCIUM ION, ... | Authors: | Zebisch, M, Pippel, J, Knapp, K, Straeter, N. | Deposit date: | 2012-09-12 | Release date: | 2012-11-28 | Last modified: | 2012-12-26 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure, 20, 2012
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